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Which phase of clinical trials determines the efficacy of a drug?
Pharmacy Pharmacology D. Pharma General Pharmacology
Q. 2 of Quiz-2138 (Que-ID : 4908)
Which phase of clinical trials determines the efficacy of a drug?
- Phase I
- Phase II
- Phase III
- Phase IV
Ans → (c)Phase III
Explanation → Phase III trials confirm the drug's effectiveness in large populations before approval.
This question is taken from this post → Pharmacist Exam MCQs – 50 Important Questions for Quick Revision - attemp/practice
More MCQs in - Pharmacist Exam MCQs – 50 Important Questions for Quick Revision
Q. 1 of Quiz-2138 (Que-ID : 4907)
Which of the following is the prodrug of dopamine?
- Levodopa
- Epinephrine
- Norepinephrine
- Serotonin
Q. 2 of Quiz-2138 (Que-ID : 4908)
Which phase of clinical trials determines the efficacy of a drug?
- Phase I
- Phase II
- Phase III
- Phase IV
Q. 3 of Quiz-2138 (Que-ID : 4909)
Which of the following drugs is an H2 receptor antagonist?
- Omeprazole
- Ranitidine
- Loratadine
- Fexofenadine
Q. 4 of Quiz-2138 (Que-ID : 4910)
What is the normal pH range of blood?
- 6.8 - 7.2
- 7.35 - 7.45
- 7.5 - 8.0
- 6.0 - 6.5
Q. 5 of Quiz-2138 (Que-ID : 4911)
Which schedule of the Drugs and Cosmetics Act regulates narcotic drugs in India?
- Schedule H
- Schedule X
- Schedule G
- Schedule C
Q. 6 of Quiz-2138 (Que-ID : 4912)
Which dosage form is designed for controlled drug release?
- Tablet
- Capsule
- Sustained-release tablet
- Powder
Q. 7 of Quiz-2138 (Que-ID : 4913)
What is the primary function of bile salts in digestion?
- Emulsification of fats
- Protein breakdown
- Carbohydrate digestion
- Acid neutralization
Q. 8 of Quiz-2138 (Que-ID : 4914)
Which vitamin deficiency causes rickets?
- Vitamin A
- Vitamin C
- Vitamin D
- Vitamin K
Q. 9 of Quiz-2138 (Que-ID : 4915)
Which instrument is used for sterilization by dry heat?
- Autoclave
- Hot air oven
- Laminar airflow
- UV chamber
Q. 10 of Quiz-2138 (Que-ID : 4916)
Which drug is commonly used in the treatment of tuberculosis?
- Rifampicin
- Amoxicillin
- Cephalexin
- Metronidazole
Q. 11 of Quiz-2138 (Que-ID : 4917)
Which polymer is used for enteric coating of tablets?
- Hydroxypropyl cellulose
- Eudragit
- Starch
- Gelatin
Q. 12 of Quiz-2138 (Que-ID : 4918)
Which of the following is a β-lactam antibiotic?
- Ciprofloxacin
- Penicillin
- Vancomycin
- Erythromycin
Q. 13 of Quiz-2138 (Que-ID : 4919)
What is the main site of drug metabolism?
- Kidney
- Liver
- Lungs
- Heart
Q. 14 of Quiz-2138 (Que-ID : 4920)
Which neurotransmitter is mainly affected in Alzheimer’s disease?
- Dopamine
- Serotonin
- Acetylcholine
- GABA
Q. 15 of Quiz-2138 (Que-ID : 4921)
Which anticoagulant is used in blood storage bags?
- Heparin
- Warfarin
- EDTA
- Citrate
Q. 16 of Quiz-2138 (Que-ID : 4922)
Which of the following is a third-generation cephalosporin?
- Cephalexin
- Ceftriaxone
- Cefuroxime
- Cefazolin
Q. 17 of Quiz-2138 (Que-ID : 4923)
Which hormone is responsible for milk ejection?
- Prolactin
- Oxytocin
- Estrogen
- Progesterone
Q. 18 of Quiz-2138 (Que-ID : 4924)
What is the normal shelf life of most pharmaceutical tablets?
- 1-2 years
- 3-5 years
- 5-7 years
- 10 years
Q. 19 of Quiz-2138 (Que-ID : 4925)
Which drug is used as an antidote for heparin overdose?
- Vitamin K
- Protamine sulfate
- EDTA
- Warfarin
Q. 20 of Quiz-2138 (Que-ID : 4926)
Which analytical technique is used for drug purity testing?
- NMR
- UV Spectroscopy
- IR Spectroscopy
- HPLC
Q. 21 of Quiz-2138 (Que-ID : 4927)
Which is an example of an aminoglycoside antibiotic?
- Tetracycline
- Amikacin
- Erythromycin
- Clindamycin
Q. 22 of Quiz-2138 (Que-ID : 4928)
Which dosage form bypasses first-pass metabolism?
- Oral tablet
- Sublingual tablet
- Capsule
- Suppository
Q. 23 of Quiz-2138 (Que-ID : 4929)
Which of these is a synthetic corticosteroid?
- Prednisolone
- Adrenaline
- Insulin
- Thyroxine
Q. 24 of Quiz-2138 (Que-ID : 4930)
Which organ is most affected by nephrotoxic drugs?
- Liver
- Heart
- Kidneys
- Lungs
Q. 25 of Quiz-2138 (Que-ID : 4931)
Which of the following is a macrolide antibiotic?
- Erythromycin
- Ciprofloxacin
- Amoxicillin
- Doxycycline
Q. 26 of Quiz-2138 (Que-ID : 4932)
Which one is a commonly used antiepileptic drug?
- Diazepam
- Phenytoin
- Paracetamol
- Ibuprofen
Q. 27 of Quiz-2138 (Que-ID : 4933)
Which of the following is used as a preservative in pharmaceutical preparations?
- Citric acid
- Chlorocresol
- Sucrose
- Starch
Q. 28 of Quiz-2138 (Que-ID : 4934)
Which gas is used for sterilizing heat-sensitive equipment?
- Nitrogen
- Carbon dioxide
- Ethylene oxide
- Oxygen
Q. 29 of Quiz-2138 (Que-ID : 4935)
What is the use of mannitol in pharmacy?
- Diuretic
- Antibiotic
- Analgesic
- Antifungal
Q. 30 of Quiz-2138 (Que-ID : 4936)
Which of the following is a sedative-hypnotic agent?
- Paracetamol
- Diazepam
- Aspirin
- Metformin
Q. 31 of Quiz-2138 (Que-ID : 4937)
Which is a commonly used emulsifying agent?
- Sucrose
- Acacia
- Magnesium sulfate
- Sodium chloride
Q. 32 of Quiz-2138 (Que-ID : 4938)
Which vitamin is synthesized in the skin by sunlight?
- Vitamin A
- Vitamin B12
- Vitamin D
- Vitamin K
Q. 33 of Quiz-2138 (Que-ID : 4939)
Which drug class does Losartan belong to?
- Beta-blockers
- Calcium channel blockers
- ACE inhibitors
- ARBs
Q. 34 of Quiz-2138 (Que-ID : 4940)
Which laboratory test evaluates kidney function?
- LFT
- ECG
- Serum creatinine
- CBC
Q. 35 of Quiz-2138 (Que-ID : 4941)
Which schedule deals with prescription drugs in India?
- Schedule H
- Schedule K
- Schedule P
- Schedule J
Q. 36 of Quiz-2138 (Que-ID : 4942)
Which organelle is called the 'powerhouse of the cell'?
- Nucleus
- Golgi apparatus
- Mitochondria
- Ribosome
Q. 37 of Quiz-2138 (Que-ID : 4943)
Which drug is used to treat hyperthyroidism?
- Levothyroxine
- Methimazole
- Insulin
- Prednisone
Q. 38 of Quiz-2138 (Que-ID : 4944)
Which electrolyte is critical for nerve impulse transmission?
- Calcium
- Magnesium
- Potassium
- Iron
Q. 39 of Quiz-2138 (Que-ID : 4945)
Which of the following is a loop diuretic?
- Spironolactone
- Furosemide
- Hydrochlorothiazide
- Amiloride
Q. 40 of Quiz-2138 (Que-ID : 4946)
Which part of the prescription contains instructions to the pharmacist?
- Superscription
- Inscription
- Subscription
- Signature
Q. 41 of Quiz-2138 (Que-ID : 4947)
What is the role of glidants in tablet formulation?
- Binders
- Disintegrants
- Flow enhancers
- Lubricants
Q. 42 of Quiz-2138 (Que-ID : 4948)
Which test is used to detect the presence of reducing sugars?
- Molisch test
- Benedict's test
- Biuret test
- Tollen's test
Q. 44 of Quiz-2138 (Que-ID : 4950)
Which enzyme breaks down proteins in the stomach?
- Amylase
- Pepsin
- Lipase
- Trypsin
Q. 45 of Quiz-2138 (Que-ID : 4951)
Which part of the plant is used in case of digitalis?
- Root
- Leaf
- Bark
- Flower
Q. 46 of Quiz-2138 (Que-ID : 4952)
Which is an example of a fixed-dose combination drug?
- Paracetamol
- Amoxicillin
- Lopinavir/Ritonavir
- Metformin
Q. 47 of Quiz-2138 (Que-ID : 4953)
Which type of immunity is passed from mother to child?
- Active immunity
- Artificial immunity
- Passive natural immunity
- Adaptive immunity
Q. 48 of Quiz-2138 (Que-ID : 4954)
Which analytical method separates mixtures based on polarity?
- UV Spectroscopy
- Chromatography
- Titration
- Electrophoresis
Q. 49 of Quiz-2138 (Que-ID : 4955)
Which drug is used for emergency contraception?
- Levonorgestrel
- Ethinylestradiol
- Misoprostol
- Mifepristone
Q. 50 of Quiz-2138 (Que-ID : 4956)
Which vitamin is essential for blood clotting?
- Vitamin A
- Vitamin D
- Vitamin E
- Vitamin K
More MCQs In - Pharmacy Pharmacology D. Pharma General Pharmacology
Q. 50 of Quiz- (Que-ID : 4956)
Which vitamin is essential for blood clotting?
- Vitamin A
- Vitamin D
- Vitamin E
- Vitamin K
Q. 8 of Quiz- (Que-ID : 2210)
Solution of Borax is used as eyewash and wet dressing for wounds is-
- 1-2% of solution
- 10-20% of solution
- 5-10% of solution
- 70-78% of solution
Q. 11 of Quiz- (Que-ID : 1820)
Which one of these is not a antiviral agent?
- Amantadine
- Idoxuridine
- Acyclovir
- Haymycin
Q. 3 of Quiz- (Que-ID : 644)
Levodopa is amino acid precursor of -
- Adrenaline
- Dopamine
- Norepinephrine
- All of these
Q. 28 of Quiz- (Que-ID : 1181)
Which is not a mineral hydrocolloid?
- Veegum
- Colloidal silica
- Colloidal alumina
- Tragacanth
Q. 24 of Quiz- (Que-ID : 667)
Which one is a cholinomimetic agent?
Which one is a cholinomimetic agent?
- Atropine
- Salbutamol
- Tolbutamide
- Acetylcholine
Directions :
A mirage is the result of -
- The reflection of light from hot sand
- Fluctuation in the refractive index of the atmosphere with height
- Increase in the refractive index of the atmosphere with height
- decrease in the refractive index of the atmosphere with height
Q. 41 of Quiz- (Que-ID : 128)
Which of the given combination has an intraction, beneficial for routine clinical use?
- Hydralazine and atenolol
- Metochlopramide and levodopa
- Quinidine and digoxine
- Furosemide and lithium carbonate
Q. 50 of Quiz- (Que-ID : 4956)
Which vitamin is essential for blood clotting?
- Vitamin A
- Vitamin D
- Vitamin E
- Vitamin K
Q. 28 of Quiz- (Que-ID : 115)
Removal of para-nitro group of chloramphenicol may
- Increases the toxicity
- Decreases bitterness
- Decreses potency
- Increases water solubility
Q. 50 of Quiz- (Que-ID : 4956)
Which vitamin is essential for blood clotting?
- Vitamin A
- Vitamin D
- Vitamin E
- Vitamin K
Q. 18 of Quiz- (Que-ID : 4924)
What is the normal shelf life of most pharmaceutical tablets?
- 1-2 years
- 3-5 years
- 5-7 years
- 10 years
Q. 12 of Quiz- (Que-ID : 655)
The sulphonamides are :
- Bactericidal in nature
- Bacteriostatic in nature
- Bactericidal only at high dose
- None of the above
Q. 11 of Quiz- (Que-ID : 406)
The most potent CNS stimulant among xanthine bases are:
- Theophylline
- Theobromine
- Caffeine
- All of the above
Q. 4 of Quiz- (Que-ID : 1551)
Generally pastes contain
- Very low percentage of insoluble solids
- Low percentage of insoluble solids
- High percentage of insoluble solids
- soluble solids
Q. 23 of Quiz- (Que-ID : 1176)
Fine droplets of nasal sprays are produced by using -
- Nebuliser
- Atomiser
- Propellent
- Sprayer
Q. 30 of Quiz- (Que-ID : 117)
Which one of the following is the initial step in the absorption of the drug from a tablet
- Deaggregation
- Diffusion
- Disintegration
- Dissolutuin
Q. 2 of Quiz- (Que-ID : 1539)
Latin term "Infricandus" means the following dosage form,
- to be spread on
- to be applied on
- to be inhaled
- to be rubbed on
Q. 3 of Quiz- (Que-ID : 1530)
The chin can be described as being on the _____ surface of the skull.
- inferior
- lateral
- superior
- ventral
Q. 17 of Quiz- (Que-ID : 519)
Which colour is permitted in soaps?
- Phthalocyanine blue
- Citrus red number 2
- Rhodamine
- All of these
Q. 1 of Quiz- (Que-ID : 4907)
Which of the following is the prodrug of dopamine?
- Levodopa
- Epinephrine
- Norepinephrine
- Serotonin
Q. 18 of Quiz- (Que-ID : 661)
Eserine acts by -
- Receptor mechanism
- Acting on cell membrane
- Drug-enzyme interactions
- None of the above
Q. 1 of Quiz- (Que-ID : 1485)
Compared to subcutaneous injection, the intramus- cular injection of drugs:
- Is more painful
- Produces faster response
- Is unsuitable for depot preparations
- Carries greater risk of anaphylactic reaction
Q. 17 of Quiz- (Que-ID : 1051)
Progesterone is secreted by
- Corpus leteum
- Testis
- Ovary
- None of the above
Q. 21 of Quiz- (Que-ID : 664)
Which one of these is used with hyoscine to induce Twilight sleep?
- Pentazocine
- Pethidine
- Diphenhydramine
- None of the above
Q. 7 of Quiz- (Que-ID : 431)
Which of the river Originates in Tibetan plateau, Enters India in J&K ?
- Ganga
- Bramaputra
- Indus
- Yamuna
Q. 24 of Quiz- (Que-ID : 4930)
Which organ is most affected by nephrotoxic drugs?
- Liver
- Heart
- Kidneys
- Lungs
Q. 1 of Quiz- (Que-ID : 411)
Suganril is common brand name for:
- Phenylbutazone
- Piroxican
- Benorylate
- Indomethacin
Q. 8 of Quiz- (Que-ID : 4914)
Which vitamin deficiency causes rickets?
- Vitamin A
- Vitamin C
- Vitamin D
- Vitamin K
Q. 19 of Quiz- (Que-ID : 4925)
Which drug is used as an antidote for heparin overdose?
- Vitamin K
- Protamine sulfate
- EDTA
- Warfarin
Q. 15 of Quiz- (Que-ID : 658)
Pyridoxine is administered with isoniazid to minimise the:
- Hepatotoxicity
- Neurotoxicity
- Nephrotoxicity
- Allergic reaction
Q. 20 of Quiz- (Que-ID : 1280)
An opthalmic solution is sterilized by-
- Autoclaving
- Sterilization by filtration
- Gaseous sterilization
- Dry heat sterilization
Directions :
Q. 4 of Quiz- (Que-ID : 1488)The most important factor governing absorption of a drug from intact skin is
- Nature of the base used in the formulation
- Lipid solubility of the drug
- Molecular weight of the drug
- Site of application
Q. 18 of Quiz- (Que-ID : 1141)
In testosterone propionate injection, vehicle is -
- Apyrogenic water
- Seasome oil
- Polyethylene glycol
- None of the above
Q. 1 of Quiz- (Que-ID : 178)
Which one is not an ester prodrug?
- Aspirin
- Benorylate
- Salsalate
- None of these
Q. 3 of Quiz- (Que-ID : 3568)
Anise fruit is obtained from-
Anise fruit is obtained from-
- piper cubeba
- Pimpenella anisum
- Apium graveolens
- none of these
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