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The member of the quinolone family that functions by inhibiting the activity of DNA gyrase, blocking DNA replication
Microbiology Pharmacist Competitive Exams
Q. The member of the quinolone family that functions by inhibiting the activity of DNA gyrase, blocking DNA replication
Ans → nalidixic acid
Explanation →
This question is taken from the test/quiz post: Microbiology Important Questions ( One Liners )-12 Pharmacy - attemp/practice
More oneliners in - Microbiology Important Questions ( One Liners )-12 Pharmacy
Q. A type of inclusion containing volutin, a polymerized inorganic phosphate that appears red when stained with methylene blue
Ans → metachromatic granule
Explanation →
Q. A virus composed of a nucleic acid core, either DNA or RNA, surrounded by a capsid
Ans → naked virus
Explanation →
Q. The the sequencing of genomic fragments from microbial communities, allowing researchers to study genes from a collection of multiple species
Ans → metagenomics
Explanation →
Q. The science of studying a collection of mRNA molecules produced from microbial communities
Ans → metatranscriptomics
Explanation →
Q. The member of the quinolone family that functions by inhibiting the activity of DNA gyrase, blocking DNA replication
Ans → nalidixic acid
Explanation →
Q. An antibacterial and antiprotozoan drug of the nitroimidazole class that is activated in anaerobic target cell and introduces DNA strand breakage, thus interfering with DNA replication in target cells
Ans → metronidazole
Explanation →
Q. A part of the upper throat (pharynx) extending from the posterior nasal cavity; carries air inhaled through the nose
Ans → nasopharynx
Explanation →
Q. Glycoprotein expressed on the surface of all nucleated cells and involved in the presentation of normal “self” antigens and foreign antigens from intracellular pathogens
Ans → MHC I molecule
Explanation →
Q. A three-dimensional structure of folded fully functional proteins
Ans → native structure
Explanation →
Q. A glycoprotein expressed only on the surface of antigen-presenting cells and involved in the presentation of foreign antigens from pathogens ingested by phagocytosis
Ans → MHC II molecule
Explanation →
Q. A lymphoid cells that recognize and destroy abnormal target cells by inducing apoptosis
Ans → natural killer cells (NK cells)
Explanation →
Q. A simple spherical arrangement of amphipathic lipid molecules with nonpolar tails aggregated within the interior and polar heads forming the outer surface
Ans → micelle
Explanation →
Q. A a stain that produces colour around the structure of interest while not coloring the structure itself
Ans → negative stain
Explanation →
Q. An organism that requires oxygen at levels lower than atmospheric concentration
Ans → microaerophile
Explanation →
Q. A herpes infection of the newborn, generally caused by infection during birth
Ans → neonatal herpes
Explanation →
More one-liners in - Microbiology
Q. Name the enzyme produced by pathogens that degrades hyaluronic acid between adjacent cells in connective tissue
Ans → hyaluronidase
Explanation →
Q. The member of the quinolone family that functions by inhibiting the activity of DNA gyrase, blocking DNA replication
Ans → nalidixic acid
Explanation →
Q. Insertion or grafting of a biological, living, inert, or radioactive material into the body.
Ans → implantation
Explanation →
Q. Test in which antigen and antisera are added to neighboring wells in an agar gel, allowing visualization of precipitin arcs
Ans → Ouchterlony assay
Explanation →
Q. Name the class of antibacterials that inhibit cell wall synthesis by binding to peptidoglycan subunits and blocking their insertion into the cell wall backbone.
Ans → glycopeptides
Explanation →
Q. Cytokines released by cells that have been infected with a virus; stimulate antiviral responses in nearby cells as well as the cells secreting the interferons
Ans → interferons
Explanation →
Q. The enzyme that is regulated by feedback inhibition in heme synthesis is
Ans → δ -Aminolevulinate synthase
Explanation →
Q. A molecule that seeks out electrons, also known as a Lewis Acid or an electron pair acceptor.
Ans → Electrophile
Explanation →
Q. The compound implicated in the development of cataract in diabetic patients is
Ans → Sorbitol
Explanation →
Q. A host in which a parasite goes through some stages of its life cycle before migrating to the definitive host
Ans → intermediate host
Explanation →
Q. This refers to protozoans that consume food particles through phagoctytosis
Ans → holozoic
Explanation →
Q. The short fragment of DNA made during lagging strand synthesis
Ans → Okazaki fragment
Explanation →
Q. Name the graph modeling the number of cells in a culture over time
Ans → growth curve
Explanation →
Q. Transport of glucose from the lumen to the intestinal mucosal cells is coupled with diffusion of
Ans → Enteropeptidase
Explanation →
Q. A a variant of PCR involving the use of fluorescence to allow for the monitoring of the increase in double-stranded template during a PCR reaction as it occurs
Ans → real-time PCR
Explanation →
Q. Muscular contractions of the gastrointestinal tract that propel ingested material through the stomach,
Ans → peristalsis
Explanation →
Q. The means of entry by a pathogen through skin or mucous membranes when these barriers are breached
Ans → parenteral route
Explanation →
Q. The phenomenon of disorganization of native protein structure is known as
Ans → Denaturation
Explanation →
Q. The bonds in protein structure that are not broken on denaturation.
Ans → Peptide bonds
Explanation →
Q. Properties of a substance that can be observed without using a chemical reaction that would change the substance.
Ans → physical property
Explanation →
Q. Small number of cells added to medium to start a culture is commonly called
Ans → inoculum
Explanation →
Q. Lipid molecules with attached sugars that are found as components of gram-negative outer membranes
Ans → lipopolysaccharide
Explanation →
Q. Process by which food is rendered free from pathogenic, toxigenic, and spoilage organisms.
Ans → appertization
Explanation →
Q. the energy required to break a particular bond by a homolytic process.
Ans → bond energy
Explanation →
Q. A compound possessing hydrophobic and hydrophilic groups in its structure is known as
Ans → Ampipathic
Explanation →
Q. Molecules that contain groups with characteristically different properties, e.g., both hydrophilic and lipophilic (hydrophobic) properties.
Ans → amphiphilic
Explanation →
Q. A type of inclusion containing volutin, a polymerized inorganic phosphate that appears red when stained with methylene blue
Ans → metachromatic granule
Explanation →
Q. Type of mutation involving the addition of one or more bases into a DNA sequence
Ans → insertion
Explanation →
Q. Sweet (often colored) dilute alcohol-based, “hydroalcoholic”, liquid used in the compounding of drugs to be taken by mouth in order to improve palatability.
Ans → elixir
Explanation →
Q. Structure of protein complexes formed by the combination of several separate polypeptides or subunits
Ans → quaternary structure
Explanation →
Q. Examples of two enzymes containing zinc are
Ans → Alcohol dehydrogenase, carbonic anhydrase
Explanation →
Q. Small number of cells added to medium to start a culture is commonly called
Ans → inoculum
Explanation →