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A Formulated preparation of molecules/drugs that are rarely if ever suitable for administration to patients without additives.
Pharmaceutics Pharmacist Competitive Exams
Q. A Formulated preparation of molecules/drugs that are rarely if ever suitable for administration to patients without additives.
Ans → dosage form
Explanation →
This question is taken from the test/quiz post: one liners Pharmaceutics| B.Pharmacy| Pharmacy file-3 - attemp/practice
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Q. An Obstacle such as coating or embedding, which acts as a factor controlling the rate of drug release.
Ans → diffusion barrier
Explanation →
Q. Name a stage in the drying of solids, above which the drying rate is linear, at which the drying rate ceases to be linear, until it reaches the equilibrium moisture content.
Ans → critical moisture content
Explanation →
Q. Formulation in which individual doses of a granulated dosage form are separated
Ans → divided granule
Explanation →
Q. Type of comparative bioavailability study designed in such a way as to take into account differences in bioavailability arising from differences between patients suffering from disease
Ans → crossover study
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Q. Powder formulation in which individual doses of a powdered dosage form are separately wrapped
Ans → divided powder
Explanation →
Q. Name term that describes a solid of regular shape and the presence of three-dimensional order on the level of atomic dimensions, for a given molecule.
Ans → crystalline
Explanation →
Q. A Formulated preparation of molecules/drugs that are rarely if ever suitable for administration to patients without additives.
Ans → dosage form
Explanation →
Q. Dosage form in which the active ingredient is insoluble in the carrier; includes aerosols, suspensions, emulsions , and foams
Ans → disperse system
Explanation →
Q. A Biologically active substance, which when biodistributed in the body is expected to modify one or more of its functions.
Ans → drug
Explanation →
Q. Solid preparation that on contact with water breaks apart by the effect of gas evolution, resulting commonly from the reaction of hydrogen carbonate with citric or tartaric acid, in order to facilitate dissolution or dispersion of the active ingredient before ingestion.
Ans → effervescent tablet
Explanation →
Q. Opposite of deliquescence; the drying of a salt solution when the vapour pressure of water in the saturated solution of a substance is greater than the partial pressure of water in the ambient air.
Ans → efflorescence
Explanation →
Q. Name a technological process, which consists of mixing or inclusion of the therapeutic substance with an excipient or their mixtures, typically as a matrix dosage form, in order to change the rate of release.
Ans → embedding
Explanation →
Q. Sweet (often colored) dilute alcohol-based, “hydroalcoholic”, liquid used in the compounding of drugs to be taken by mouth in order to improve palatability.
Ans → elixir
Explanation →
Q. The process of separating the lighter particles of a powder from the heavier ones by means of an upward-directed stream of fluid
Ans → elutriation
Explanation →
Q. Name a substance that loses water to form a lower hydrate or becomes anhydrous spontaneously.
Ans → efflorescent
Explanation →
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Q. Substrate level phosphorylation in citric acid cycle is catalysed by the enzyme
Ans → Succinate thiokinase
Explanation →
Q. Small sterile usually polymeric matrices, pellets, or particles for insertion or implanting into the body by surgical means or by injection to help achieve sustained release.
Ans → implants
Explanation →
Q. substance(s) is(are) involved in the regulation of plasma calcium level
Ans → Calcitriol , Parathyroid hormone, Calcitonin
Explanation →
Q. This refers to a cytokine signal released from a cell to a receptor on a nearby cell
Ans → paracrine function
Explanation →
Q. The following anticoagulant binds with Ca2+ and prevents blood clotting
Ans → Oxalate
Explanation →
Q. Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Ans → pseudopolymorph
Explanation →
Q. The Threshold detergent concentration at which micelle formation begins in the bulk phase is called
Ans → critical micelle concentration (cmc)
Explanation →
Q. a term which may be applied to any asymmetric object or molecule. The property of non-identity of an object with its mirror image
Ans → chirality
Explanation →
Q. A staining technique in which labeled antibodies are bound to specific cells in a tissue section
Ans → immunohistochemistry (IHC)
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Q. A a term applied to an atom or molecule having one or more free valencies.
Ans → radical
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Q. Name the study that compares entire genomes, including the complete set of genes, their nucleotide sequence and organization
Ans → Genomics
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Q. Structure of protein complexes formed by the combination of several separate polypeptides or subunits
Ans → quaternary structure
Explanation →
Q. Muscular contractions of the gastrointestinal tract that propel ingested material through the stomach,
Ans → peristalsis
Explanation →
Q. Antihelminthic drug of the benzimidazole class that binds to helminthic β-tubulin, preventing microtubule formation
Ans → mebendazole
Explanation →
Q. Technique that uses living organisms to make or modify products, to improve plants or animals, or to develop microorganisms for specific uses
Ans → biotechnology
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Q. When particles move to a lower area of concentration from a high area of concentration.
Ans → diffusion
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Q. The process whereby a molecule is split into simpler fragments which may be smaller molecules, atoms, free radicals or ions.
Ans → dissociation
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Q. Larger nucleus in ciliate protists that have two nuclei; polyploid with a reduced genome of metabolic genes and derived from the micronucleus
Ans → macronucleus
Explanation →
Q. Type of mutation involving the addition of one or more bases into a DNA sequence
Ans → insertion
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Q. The immunity which is produced by injecting a vaccine in the the body is termed as _______.
Ans → Artificial acquired active immunity
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Q. The shorter identical peptide chains of an antibody molecule (two per antibody monomer), composed of variable and constant region segments
Ans → light chains
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Q. Process of enclosing a drug in a (micro or nano) particle (capsule, liposome, polymer).
Ans → encapsulation
Explanation →
Q. The carbohydrate that is taken as a reference for writing the configuration of others
Ans → Glyceraldehydes
Explanation →
Q. The first stage of acute disease, during which the pathogen begins multiplying in the host and signs and symptoms are not observable
Ans → incubation period
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Q. A term applied to the combination of molecules of a substance with one another to form more complex systems.
Ans → association
Explanation →
Q. The sideways projection of a carbon-carbon single bond and the attached substituents.
Ans → sawhorse projection
Explanation →
Q. Antibodies that makes bacteria more susceptible to phagocytosis are called ______.
Ans → opsonins
Explanation →
Q. Molecules that exist only during a chemical reaction; not before or after the reaction.
Ans → intermediate
Explanation →
Q. A group of common sexually transmitted viruses that may be associated with genital warts or with cervical cancer
Ans → human papillomavirus (HPV)
Explanation →