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Name a technological process, which consists of mixing or inclusion of the therapeutic substance with an excipient or their mixtures, typically as a matrix dosage form, in order to change the rate of release.
Pharmaceutics Pharmacist Competitive Exams
Q. Name a technological process, which consists of mixing or inclusion of the therapeutic substance with an excipient or their mixtures, typically as a matrix dosage form, in order to change the rate of release.
Ans → embedding
Explanation →
This question is taken from the test/quiz post: one liners Pharmaceutics| B.Pharmacy| Pharmacy file-3 - attemp/practice
More oneliners in - one liners Pharmaceutics| B.Pharmacy| Pharmacy file-3
Q. An Obstacle such as coating or embedding, which acts as a factor controlling the rate of drug release.
Ans → diffusion barrier
Explanation →
Q. Name a stage in the drying of solids, above which the drying rate is linear, at which the drying rate ceases to be linear, until it reaches the equilibrium moisture content.
Ans → critical moisture content
Explanation →
Q. Formulation in which individual doses of a granulated dosage form are separated
Ans → divided granule
Explanation →
Q. Type of comparative bioavailability study designed in such a way as to take into account differences in bioavailability arising from differences between patients suffering from disease
Ans → crossover study
Explanation →
Q. Powder formulation in which individual doses of a powdered dosage form are separately wrapped
Ans → divided powder
Explanation →
Q. Name term that describes a solid of regular shape and the presence of three-dimensional order on the level of atomic dimensions, for a given molecule.
Ans → crystalline
Explanation →
Q. A Formulated preparation of molecules/drugs that are rarely if ever suitable for administration to patients without additives.
Ans → dosage form
Explanation →
Q. Dosage form in which the active ingredient is insoluble in the carrier; includes aerosols, suspensions, emulsions , and foams
Ans → disperse system
Explanation →
Q. A Biologically active substance, which when biodistributed in the body is expected to modify one or more of its functions.
Ans → drug
Explanation →
Q. Solid preparation that on contact with water breaks apart by the effect of gas evolution, resulting commonly from the reaction of hydrogen carbonate with citric or tartaric acid, in order to facilitate dissolution or dispersion of the active ingredient before ingestion.
Ans → effervescent tablet
Explanation →
Q. Opposite of deliquescence; the drying of a salt solution when the vapour pressure of water in the saturated solution of a substance is greater than the partial pressure of water in the ambient air.
Ans → efflorescence
Explanation →
Q. Name a technological process, which consists of mixing or inclusion of the therapeutic substance with an excipient or their mixtures, typically as a matrix dosage form, in order to change the rate of release.
Ans → embedding
Explanation →
Q. Sweet (often colored) dilute alcohol-based, “hydroalcoholic”, liquid used in the compounding of drugs to be taken by mouth in order to improve palatability.
Ans → elixir
Explanation →
Q. The process of separating the lighter particles of a powder from the heavier ones by means of an upward-directed stream of fluid
Ans → elutriation
Explanation →
Q. Name a substance that loses water to form a lower hydrate or becomes anhydrous spontaneously.
Ans → efflorescent
Explanation →
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Q. The successful colonization of a microorganism within a host is called as
Ans → infection
Explanation →
Q. The long chain fatty acids (C26—C35) are not oxidized due to the absence of peroxisomes. This disorder is known as
Ans → Zellweger syndrome
Explanation →
Q. Name the compound that is increased in RBC of anemic patients to facilitate the supply of O2 to the tissues
Ans → 2,3-Bisphosphoglycerate
Explanation →
Q. The enzyme that is regulated by feedback inhibition in heme synthesis is
Ans → δ -Aminolevulinate synthase
Explanation →
Q. The science and study of the ways in which the pharmaceutical formulation of administered agents can influence their pharmacodynamic and pharmacokinetic behaviour.
Ans → Biopharmaceutics
Explanation →
Q. Dosage form comprising several elements (e.g., microspheres or coated pellets) dif- fering in the rate of drug release.
Ans → multi compartment formulation
Explanation →
Q. The mantous test is done to detect the immunity or susceptibility to _____ .
Ans → Tuberculosis
Explanation →
Q. Chemical alteration of an agent (drug) that occurs by virtue of the sojourn of the agent in a biological system.
Ans → Biotransformation
Explanation →
Q. Process of agglomeration that converts fine powders or granules of bulk drugs and excipients into small, free-flowing, spherical, or semi-spherical units, referred to as pellets.
Ans → pelletization
Explanation →
Q. The immunity which is produced by injecting a vaccine in the the body is termed as _______.
Ans → Artificial acquired active immunity
Explanation →
Q. The migration of a double bond in a 3-carbon system from carbon atoms one and two to carbon atoms two and three
Ans → allylic rearrangement
Explanation →
Q. The backbone of nucleic acid structure is constructed by
Ans → Phosphodiester bridges
Explanation →
Q. Dosage form in which the active ingredient is insoluble in the carrier; includes aerosols, suspensions, emulsions , and foams
Ans → disperse system
Explanation →
Q. A a term applied to an atom or molecule having one or more free valencies.
Ans → radical
Explanation →
Q. Name the term that refers to a polar molecule or portion of a molecule capable of strong attraction to water molecules
Ans → hydrophilic
Explanation →
Q. Powder particles, which have been aggregated to form larger irregular particles, usually of 0.5–2 mm diameter.
Ans → granules
Explanation →
Q. When a complex is formed between a metal ion and an a ligand in solution, the equilibrium may be expressed by a constant which is related to the free energy change for the process
Ans → stability constant
Explanation →
Q. Name the capillary bed in the nephron of the kidney that filters blood to form urine
Ans → glomerulus
Explanation →
Q. The movement of chemicals (drugs) into, through, and out of biological organisms or their parts.
Ans → Biotranslocation
Explanation →
Q. Salivary -amylase becomes inactive in the stomach primarily due to
Ans → Inactivation by low pH
Explanation →
Q. The term given to organic molecules which contain no multiple bonds.
Ans → saturated
Explanation →
Q. Which are the essential fatty acids that need to be supplied in the diet.
Ans → PUFA
Explanation →
Q. A lymphoid cells that recognize and destroy abnormal target cells by inducing apoptosis
Ans → natural killer cells (NK cells)
Explanation →
Q. The number of mg of KOH required to hydrolyse 1 g fat or oil is known as
Ans → Saponification number
Explanation →
Q. The major dietary energy sources, besides their involvement in cell structure and various other functions is
Ans → Carbohydrates
Explanation →
Q. When a compound is changed into water, heat, and CO2 as a result of combining with oxygen.
Ans → combustion
Explanation →
Q. Process of agglomeration that converts fine powders or granules of bulk drugs and excipients into small, free-flowing, spherical, or semi-spherical units, referred to as pellets.
Ans → pelletization
Explanation →
Q. Procedure for estimating the concentration or biological activity of a substance by measuring its effect on a living system compared to a standard system
Ans → bioassay
Explanation →
Q. Name a membrane-bound organelle (not part of the endomembrane system) that produces hydrogen peroxide to break down various types of molecules;
Ans → peroxisome
Explanation →
Q. Name the process producing only lactic acid as a fermentation product
Ans → homolactic fermentation
Explanation →