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Process of enclosing a drug in a (micro or nano) particle (capsule, liposome, polymer).
Pharmaceutics Pharmacist Competitive Exams
Q. Process of enclosing a drug in a (micro or nano) particle (capsule, liposome, polymer).
Ans → encapsulation
Explanation →
This question is taken from the test/quiz post: one liners Pharmaceutics| B.Pharmacy| Pharmacy file-4 - attemp/practice
More oneliners in - one liners Pharmaceutics| B.Pharmacy| Pharmacy file-4
Q. The process of separating the lighter particles of a powder from the heavier ones by means of an up- ward-directed stream of fluid (gas or liquid).
Ans → elutriation
Explanation →
Q. Technological process, which consists of mixing or inclusion of the therapeutic substance with an excipient or their mixtures,
Ans → embedding
Explanation →
Q. Process of enclosing a drug in a (micro or nano) particle (capsule, liposome, polymer).
Ans → encapsulation
Explanation →
Q. Non-fluid colloidal network or polymer network that is expanded throughout its whole volume by a fluid.
Ans → gel
Explanation →
Q. Solutions (aqueous or oily), emulsions, or suspensions for rectal administration of medicaments for cleansing, diagnostic, or therapeutic purposes.
Ans → enemas
Explanation →
Q. Used on tablets, granules, pellets, and capsules to make them resistant to gastric fluids but designed to disintegrate, disrupt, or dissolve when the preparation enters the duodenum.
Ans → enteric coating
Explanation →
Q. Use of products containing genetic material (e.g., pDNA, antisense DNA, si RNA) to treat a disease or condition, or to modify or manipulate the expression of genetic material or to alter the biological properties of living cells.
Ans → gene therapy
Explanation →
Q. Summary of operations carried out to convert a pharmacologically active compound into a dosage form suitable for administration.
Ans → formulation
Explanation →
Q. Powder particles, which have been aggregated to form larger irregular particles, usually of 0.5–2 mm diameter.
Ans → granules
Explanation →
Q. The Process of contact and adhesion whereby particles in dispersion form larger-size clusters.
Ans → flocculation
Explanation →
Q. Process in which powder particles are made to aggregate to larger particles called granules.
Ans → granulation
Explanation →
Q. An aqueous solution used for the prevention and treatment of mouth and throat infections.
Ans → gargle
Explanation →
Q. Pace at which a drug along with the stomach content leaves and enters the duodenum.
Ans → gastric emptying rate
Explanation →
Q. Time required for the concentration of a reactant in a given reaction to reach a value that is the arith- metic mean of its initial and final (equilibrium) values.
Ans → half life
Explanation →
Q. Crystalline form of a compound in which water molecules are part of the crystal structure.
Ans → hydrate
Explanation →
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Q. Close, tight aggregation of colloid particles, emulsion droplets, suspension particles, which are difficult to redisperse.
Ans → coagulation
Explanation →
Q. The childrens in the age group between 2-5 years are susceptible to _______ disease.
Ans → Diphtheria
Explanation →
Q. Insertion or grafting of a biological, living, inert, or radioactive material into the body.
Ans → implantation
Explanation →
Q. The disease characterized by impairment in the absorption of neutral amino acids
Ans → Hartnup’s disease
Explanation →
Q. Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.
Ans →
Explanation →
Q. Solid substances that are not crystals. These solids consist of randomly oriented molecules. Solids without definite shape consist of randomly oriented molecules.
Ans → amorphous
Explanation →
Q. Name a substance that loses water to form a lower hydrate or becomes anhydrous spontaneously.
Ans → efflorescent
Explanation →
Q. Exploratory activity that begins early in pharmaceutics, involving studies designed to determine the compatibility of excipients with the active substance for a biopharmaceutical; physicochemical and bioanalytical investigation
Ans → preformulation
Explanation →
Q. The enzyme defect in acute intermittent porphyria
Ans → Uroporphyrinogen synthase I
Explanation →
Q. The most important enzyme involved in oxidative deamination is
Ans → Glutamate dehydrogenase
Explanation →
Q. The majority of bacterial vaccines are stored at a temperature between ___ _____.
Ans → 2 ℃ to 8 ℃
Explanation →
Q. Under physiological condition, the DNA structure is predominantly in the form
Ans → β-Form
Explanation →
Q. Name a microorganism that has an optimum growth temperature close to the temperature of boiling water
Ans → hyperthermophile
Explanation →
Q. The mechanism for making ATP that uses the potential energy stored within an electrochemical gradient to add Pi to ADP
Ans → oxidative phosphorylation
Explanation →
Q. Non-fluid colloidal network or polymer network that is expanded throughout its whole volume by a fluid.
Ans → gel
Explanation →
Q. The lipoproteins synthesized in the intestinal mucosal cells from the absorbed lipids are
Ans → Chylomicrons
Explanation →
Q. A process in which the forward reaction can reach an equilibrium with the reverse reaction.
Ans → reversible process
Explanation →
Q. The shorter identical peptide chains of an antibody molecule (two per antibody monomer), composed of variable and constant region segments
Ans → light chains
Explanation →
Q. Name the antiviral drug that blocks the fusion of HIV receptors to the coreceptors required for virus entry into the cell
Ans → fusion inhibitor
Explanation →
Q. The isomerism associated with unsaturated fatty acids
Ans → Geometric isomerism (cis-trans isomerism)
Explanation →
Q. A formal non-ambiguous, nomenclature system for the assignment of absolute configuration of structure to chiral atoms, using the Cahn, Ingold and Prelog priority rules.
Ans → R,S convention
Explanation →
Q. Consists of several different layers that are compressed on top of each other, to form a single tablet composed of two or more layers.
Ans → multilayer tablet
Explanation →
Q. The long chain fatty acids (C26—C35) are not oxidized due to the absence of peroxisomes. This disorder is known as
Ans → Zellweger syndrome
Explanation →
Q. Close, tight aggregation of colloid particles, emulsion droplets, suspension particles, which are difficult to redisperse.
Ans → coagulation
Explanation →
Q. Molecules that have the same molecular formula and sequence of atoms yet differ in their 3-D orientation.
Ans → Stereoisomer
Explanation →
Q. Usually water or low-molecular-weight alcohols or compounds, used in topical applications and in wet granulation, for the production of tablets.
Ans → moistening agents
Explanation →
Q. Usually water or low-molecular-weight alcohols or compounds, used in topical applications and in wet granulation, for the production of tablets.
Ans → moistening agents
Explanation →
Q. An animal that transfers a pathogen from one host to another or from a reservoir to a host without being infected by the pathogen itself
Ans → mechanical vector
Explanation →
Q. An organism that requires oxygen at levels lower than atmospheric concentration
Ans → microaerophile
Explanation →
Q. Name a differential staining technique that distinguishes bacteria based upon their cell wall structure
Ans → Gram stain procedure
Explanation →
Q. The first stage of acute disease, during which the pathogen begins multiplying in the host and signs and symptoms are not observable
Ans → incubation period
Explanation →
Q. Number that expresses the reduction in the numbers of a microorganism, brought about by a sterilizaion process.
Ans → inactivation factor (IF)
Explanation →
Q. Tablet, which does not contain a disintegrant and which is sucked to dissolve in the mouth to produce either a local (e.g., antiseptic) or systemic (e.g., vitamins) effect.
Ans → lozenge
Explanation →
Q. Used as processing aid in tablet and capsule manufacturing, to facilitate the movement of the formulation into the dye and punch and to reduce the energy of compression.
Ans → lubricant
Explanation →
Q. Technological process, which consists of mixing or inclusion of the therapeutic substance with an excipient or their mixtures,
Ans → embedding
Explanation →
Q. Summary of operations carried out to convert a pharmacologically active compound into a dosage form suitable for administration.
Ans → formulation
Explanation →
Q. Name a stage in the drying of solids, above which the drying rate is linear, at which the drying rate ceases to be linear, until it reaches the equilibrium moisture content.
Ans → critical moisture content
Explanation →