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Chemically modified form of a pharmacologically active compound that has to undergo biochemical or chemical transformation before exhibiting its pharmacological effect.
Pharmaceutics Pharmacist Competitive Exams
Q. Chemically modified form of a pharmacologically active compound that has to undergo biochemical or chemical transformation before exhibiting its pharmacological effect.
Ans → prodrug
Explanation →
This question is taken from the test/quiz post: One liners Pharmaceutics| B.Pharmacy| Pharmacy file-7 - attemp/practice
More oneliners in - One liners Pharmaceutics| B.Pharmacy| Pharmacy file-7
Q. Chemically modified form of a pharmacologically active compound that has to undergo biochemical or chemical transformation before exhibiting its pharmacological effect.
Ans → prodrug
Explanation →
Q. Process that differentiates or separates solid particles according to their size using a meshed or perfo- rated device.
Ans → sieving
Explanation →
Q. Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Ans → pseudopolymorph
Explanation →
Q. Method by which powder particles are compressed into a large tablet, called a slug, which is subse- quently dry-screened and compressed into a tablet.
Ans → slugging
Explanation →
Q. Measure of the fraction of a given drug that is absorbed intact into the systemic circulation from a dosage form, relative to a recognized, clinically proven, standard dosage form of that drug.
Ans → relative bioavailability
Explanation →
Q. Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.
Ans →
Explanation →
Q. Transition of a suspension of solid, usually colloid, particles in a liquid (sol) to an apparent solid, jelly- like material
Ans → sol-gel transition
Explanation →
Q. Usually small, flat, and soft tablets, which are designed to be placed under the tongue to allow direct absorption of the active ingredient through the mucosa for systemic effect.
Ans → sublingual tablets
Explanation →
Q. Additives making a substance soluble or more soluble, especially in water.
Ans → solubilizing agents
Explanation →
Q. Destruction or removal of microorganisms in or about an object, e.g., by steam, chemical agents (alcohol, phenol, ethylene oxide gas), high-velocity electron bombardment, gamma or ultraviolet light radiation or filtration.
Ans → sterilization
Explanation →
Q. Crystalline form of a compound in which one or more solvent molecules are part of the crystal strucure.
Ans → solvate
Explanation →
Q. Condition of being aseptic, or statistically free from living microorganisms and their spores.
Ans → sterility
Explanation →
Q. Process of making dense, spherical pellets by means of special spheronizing or pelletizing equipment.
Ans → spheronization
Explanation →
More one-liners in - Pharmaceutics
Q. An instrument used to measure the amount of rotation of plane polarized light by a compound, generally prepared in a solution
Ans → polarimeter
Explanation →
Q. A substance that cannot be divded chemically into component substances.
Ans → element
Explanation →
Q. The movement of chemicals (drugs) into, through, and out of biological organisms or their parts.
Ans → Biotranslocation
Explanation →
Q. A term applied an object or molecule that does not possess symmetry.
Ans → asymmetry
Explanation →
Q. Measure of the fraction of a given drug that is absorbed intact into the systemic circulation from a dosage form, relative to a recognized, clinically proven, standard dosage form of that drug.
Ans → relative bioavailability
Explanation →
Q. Concentration of a drug that must be achieved in the plasma before any desired therapeutic or pharmacological effect can be obtained.
Ans → minimum effective plasma concentration
Explanation →
Q. A compound released from a natural killer cell that creates pores in the target cell through which other toxins (particularly granzymes) can gain access to the cytoplasm
Ans → perforin
Explanation →
Q. Crystalline form of a compound in which one or more solvent molecules are part of the crystal strucure.
Ans → solvate
Explanation →
Q. Additives making a substance soluble or more soluble, especially in water.
Ans → solubilizing agents
Explanation →
Q. A group of common sexually transmitted viruses that may be associated with genital warts or with cervical cancer
Ans → human papillomavirus (HPV)
Explanation →
Q. Initial, typically larger than the maintenance dose of a drug given to a patient at the start of pharmacotherapy.
Ans → loading dose
Explanation →
Q. The phenomenon of disorganization of native protein structure is known as
Ans → Denaturation
Explanation →
Q. Sweet (often colored) dilute alcohol-based, “hydroalcoholic”, liquid used in the compounding of drugs to be taken by mouth in order to improve palatability.
Ans → elixir
Explanation →
Q. Name the class of antifungal drugs that inhibit ergosterol biosynthesis
Ans → imidazoles
Explanation →
Q. Defined for powders used pharmaceutically, according to particle sizes.
Ans → powder grades
Explanation →
Q. the angle between groups attached on adjacent carbon atoms when viewed in a Newman projection.
Ans → dihedral angle
Explanation →
Q. Inflammation of the conjunctiva in newborns caused by Chlamydia trachomatis transmitted during childbirth is
Ans → inclusion conjunctivitis
Explanation →
Q. Muscle glycogen does not directly contribute to blood glucose due to absence of the enyme
Ans → Absence of glucose 6-phosphatase
Explanation →
Q. Antihelminthic drug of the benzimidazole class that binds to helminthic β-tubulin, preventing microtubule formation
Ans → mebendazole
Explanation →
Q. The disorder in which the patients have an irresistible urge to bite their fingers and lips is
Ans → Lesch-Nyhan syndrome
Explanation →
Q. Name the organism that uses fixed organic carbon compounds as its carbon source
Ans → heterotroph
Explanation →
Q. A a term applied to an atom or molecule having one or more free valencies.
Ans → radical
Explanation →
Q. The compound that facilitates the release of O2 from oxyhemoglobin
Ans → C1– , H+ , 2, 3-BPG
Explanation →
Q. Process of making dense, spherical pellets by means of special spheronizing or pelletizing equipment.
Ans → spheronization
Explanation →
Q. The inorganic element found in the structure of majority of high-energy compounds
Ans → Phosphorus
Explanation →
Q. Introduction of genetic material from one organism to another organism within the same generation
Ans → horizontal gene transfer
Explanation →
Q. Having numerous flagella covering the entire surface of a bacterial cell is known as
Ans → peritrichous
Explanation →
Q. The process by which DNA from one organism is cut and new pieces of foreign DNA from a second organism are inserted,
Ans → recombinant DNA technology
Explanation →
Q. Tablet, which does not contain a disintegrant and which is sucked to dissolve in the mouth to produce either a local (e.g., antiseptic) or systemic (e.g., vitamins) effect.
Ans → lozenge
Explanation →
Q. A host in which a parasite goes through some stages of its life cycle before migrating to the definitive host
Ans → intermediate host
Explanation →