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Method by which powder particles are compressed into a large tablet, called a slug, which is subse- quently dry-screened and compressed into a tablet.
Pharmaceutics Pharmacist Competitive Exams
Q. Method by which powder particles are compressed into a large tablet, called a slug, which is subse- quently dry-screened and compressed into a tablet.
Ans → slugging
Explanation →
This question is taken from the test/quiz post: One liners Pharmaceutics| B.Pharmacy| Pharmacy file-7 - attemp/practice
More oneliners in - One liners Pharmaceutics| B.Pharmacy| Pharmacy file-7
Q. Chemically modified form of a pharmacologically active compound that has to undergo biochemical or chemical transformation before exhibiting its pharmacological effect.
Ans → prodrug
Explanation →
Q. Process that differentiates or separates solid particles according to their size using a meshed or perfo- rated device.
Ans → sieving
Explanation →
Q. Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Ans → pseudopolymorph
Explanation →
Q. Method by which powder particles are compressed into a large tablet, called a slug, which is subse- quently dry-screened and compressed into a tablet.
Ans → slugging
Explanation →
Q. Measure of the fraction of a given drug that is absorbed intact into the systemic circulation from a dosage form, relative to a recognized, clinically proven, standard dosage form of that drug.
Ans → relative bioavailability
Explanation →
Q. Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.
Ans →
Explanation →
Q. Transition of a suspension of solid, usually colloid, particles in a liquid (sol) to an apparent solid, jelly- like material
Ans → sol-gel transition
Explanation →
Q. Usually small, flat, and soft tablets, which are designed to be placed under the tongue to allow direct absorption of the active ingredient through the mucosa for systemic effect.
Ans → sublingual tablets
Explanation →
Q. Additives making a substance soluble or more soluble, especially in water.
Ans → solubilizing agents
Explanation →
Q. Destruction or removal of microorganisms in or about an object, e.g., by steam, chemical agents (alcohol, phenol, ethylene oxide gas), high-velocity electron bombardment, gamma or ultraviolet light radiation or filtration.
Ans → sterilization
Explanation →
Q. Crystalline form of a compound in which one or more solvent molecules are part of the crystal strucure.
Ans → solvate
Explanation →
Q. Condition of being aseptic, or statistically free from living microorganisms and their spores.
Ans → sterility
Explanation →
Q. Process of making dense, spherical pellets by means of special spheronizing or pelletizing equipment.
Ans → spheronization
Explanation →
More one-liners in - Pharmaceutics
Q. Use of products containing genetic material (e.g., pDNA, antisense DNA, si RNA) to treat a disease or condition, or to modify or manipulate the expression of genetic material or to alter the biological properties of living cells.
Ans → gene therapy
Explanation →
Q. Two electrons that are not shared between atoms within a molecule.
Ans → lone pair/unshared pair
Explanation →
Q. Greasy, semi-solid preparation for external application, often anhydrous, containing dissolved or dispersed medicaments.
Ans → ointment
Explanation →
Q. The member of the quinolone family that functions by inhibiting the activity of DNA gyrase, blocking DNA replication
Ans → nalidixic acid
Explanation →
Q. The number of mg of KOH required to hydrolyse 1 g fat or oil is known as
Ans → Saponification number
Explanation →
Q. The cofactor required for the conversion of phenylalanine to tyrosine is
Ans → Tetrahydrobiopterin
Explanation →
Q. DNA-binding proteins found in eukaryotes and archaea that aid in orderly packaging of chromosomal DNA
Ans → histones
Explanation →
Q. Name the adaptive immunity mediated by antibodies produced by B cells
Ans → humoral immunity
Explanation →
Q. Name the large group of antigens bound by antibodies; large enough to settle out of fluid suspension
Ans → immune complex
Explanation →
Q. Time required for the concentration of a reactant in a given reaction to reach a value that is the arith- metic mean of its initial and final (equilibrium) values.
Ans → half life
Explanation →
Q. The two final products in the -oxidation of odd chain fatty acids are
Ans → Acetyl CoA and propionyl CoA
Explanation →
Q. Consists of several different layers that are compressed on top of each other, to form a single tablet composed of two or more layers.
Ans → multilayer tablet
Explanation →
Q. Process of agglomeration that converts fine powders or granules of bulk drugs and excipients into small, free-flowing, spherical, or semi-spherical units, referred to as pellets.
Ans → pelletization
Explanation →
Q. A chemical reaction after which the resulting agents cannot be changed back into the reactions ingredients.
Ans → irreversible reaction
Explanation →
Q. A bond formed from the electrostatic attraction between ions with different charges. This typically consists of a metal (cation) and a nonmetal (anion). A metal loses electrons to form a cation and some non-metal gains those electrons to form an anion.
Ans → Ionic Bond
Explanation →
Q. Name the most serious stage of pertussis (whooping cough), characterized by severe and prolonged coughing spells
Ans → paroxysmal stage
Explanation →
Q. Process in which powder particles are made to aggregate to larger particles called granules.
Ans → granulation
Explanation →
Q. Name the formation, development, and differentiation of blood cells from pluripotent hematopoietic stem cells
Ans → hematopoiesis
Explanation →
Q. An aromatic molecule or ion possesses aromaticity. Aromaticity is the special property of planar (or nearly planar) cyclic, conjugated systems having (4n+2) conjugated pi electrons.
Ans → aromatic
Explanation →
Q. Destruction or removal of microorganisms in or about an object, e.g., by steam, chemical agents (alcohol, phenol, ethylene oxide gas), high-velocity electron bombardment, gamma or ultraviolet light radiation or filtration.
Ans → sterilization
Explanation →
Q. Science of preparation of drugs, dosage forms, and drug delivery systems taking into account the pharmacokinetics and pharmacodynamics of the drug as well as its physical and chemical properties.
Ans → pharmaceutics
Explanation →
Q. Technique that uses living organisms to make or modify products, to improve plants or animals, or to develop microorganisms for specific uses
Ans → biotechnology
Explanation →
Q. Reversal of coagulation or flocculation, i.e., the dispersion of aggregates to form a stable colloidal suspension or emulsion.
Ans → deflocculation
Explanation →
Q. Larger nucleus in ciliate protists that have two nuclei; polyploid with a reduced genome of metabolic genes and derived from the micronucleus
Ans → macronucleus
Explanation →
Q. Name a toxin that affects cell membrane function by either forming pores or disrupting the phospholipid bilayer
Ans → membrane-disrupting toxin
Explanation →
Q. Chemically modified form of a pharmacologically active compound that has to undergo biochemical or chemical transformation before exhibiting its pharmacological effect.
Ans → prodrug
Explanation →
Q. The base pair G-C is more stable and stronger than A-T due to
Ans → 3 Hydrogen bonds
Explanation →
Q. This refers to protozoans that consume food particles through phagoctytosis
Ans → holozoic
Explanation →