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Crystalline form of a compound in which one or more solvent molecules are part of the crystal strucure.
Pharmaceutics Pharmacist Competitive Exams
Q. Crystalline form of a compound in which one or more solvent molecules are part of the crystal strucure.
Ans → solvate
Explanation →
This question is taken from the test/quiz post: One liners Pharmaceutics| B.Pharmacy| Pharmacy file-7 - attemp/practice
More oneliners in - One liners Pharmaceutics| B.Pharmacy| Pharmacy file-7
Q. Chemically modified form of a pharmacologically active compound that has to undergo biochemical or chemical transformation before exhibiting its pharmacological effect.
Ans → prodrug
Explanation →
Q. Process that differentiates or separates solid particles according to their size using a meshed or perfo- rated device.
Ans → sieving
Explanation →
Q. Different crystalline form of a solvated compound that differ in the identity and/or the stoichiometry of the solvating molecule.
Ans → pseudopolymorph
Explanation →
Q. Method by which powder particles are compressed into a large tablet, called a slug, which is subse- quently dry-screened and compressed into a tablet.
Ans → slugging
Explanation →
Q. Measure of the fraction of a given drug that is absorbed intact into the systemic circulation from a dosage form, relative to a recognized, clinically proven, standard dosage form of that drug.
Ans → relative bioavailability
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Q. Dosage form, semi-solid, used for the administration of drugs via the rectal route, for systemic or local effect.
Ans →
Explanation →
Q. Transition of a suspension of solid, usually colloid, particles in a liquid (sol) to an apparent solid, jelly- like material
Ans → sol-gel transition
Explanation →
Q. Usually small, flat, and soft tablets, which are designed to be placed under the tongue to allow direct absorption of the active ingredient through the mucosa for systemic effect.
Ans → sublingual tablets
Explanation →
Q. Additives making a substance soluble or more soluble, especially in water.
Ans → solubilizing agents
Explanation →
Q. Destruction or removal of microorganisms in or about an object, e.g., by steam, chemical agents (alcohol, phenol, ethylene oxide gas), high-velocity electron bombardment, gamma or ultraviolet light radiation or filtration.
Ans → sterilization
Explanation →
Q. Crystalline form of a compound in which one or more solvent molecules are part of the crystal strucure.
Ans → solvate
Explanation →
Q. Condition of being aseptic, or statistically free from living microorganisms and their spores.
Ans → sterility
Explanation →
Q. Process of making dense, spherical pellets by means of special spheronizing or pelletizing equipment.
Ans → spheronization
Explanation →
More one-liners in - Pharmaceutics
Q. The compound that facilitates the release of O2 from oxyhemoglobin
Ans → C1– , H+ , 2, 3-BPG
Explanation →
Q. Type of comparative bioavailability study designed in such a way as to take into account differences in bioavailability arising from differences between patients suffering from disease
Ans → crossover study
Explanation →
Q. The major component of acute phase proteins used for the evaluation of acute phase response
Ans → C-reactive protein
Explanation →
Q. An overall reaction in which an electrophile binds to a substrate with the expulsion of another electrophile is known as
Ans → electrophilic substitution
Explanation →
Q. An interval before exponential growth of a microbial population during which cells adjust to a new environment
Ans → lag phase
Explanation →
Q. The ability of electrons to "shuffle," or alternate, between bonds, making the molecule extremely stable. The best example of this is benzene.
Ans → Resonance
Explanation →
Q. Refers to a nonpolar molecule or portion of a molecule not capable of strong attraction to water molecules
Ans → hydrophobic
Explanation →
Q. A chemical processes in which the proportion of more electronegative substituents is decreased, or the charge is made more negative, or the oxidation number is lowered.
Ans → reduction
Explanation →
Q. The ‘parent’ nucleotide synthesized in the biosynthesis of purines is
Ans → Inosine monophosphate
Explanation →
Q. The process wherein orbitals of similar energies are combined to form a set of equivalent ‘hybrid’ orbital.
Ans → hybridization
Explanation →
Q. An equimolar mixture of the two enantiomeric isomers of a compound.
Ans → racemic mixture
Explanation →
Q. Crystalline form of a compound in which water molecules are part of the crystal structure.
Ans → hydrate
Explanation →
Q. Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve extended release.
Ans → matrix formulation
Explanation →
Q. Vaccine composed of whole pathogen cells or viruses that have been killed or inactivated through treatment with heat, radiation, or chemicals
Ans → inactivated vaccine
Explanation →
Q. An adaptive immune defenses received from another individual or animal
Ans → passive immunity
Explanation →
Q. Name the graph modeling the number of cells in a culture over time
Ans → growth curve
Explanation →
Q. Name the compound that is increased in RBC of anemic patients to facilitate the supply of O2 to the tissues
Ans → 2,3-Bisphosphoglycerate
Explanation →
Q. Virus, therapeutic serum, toxin, antitoxin, or analogous product applicable to the prevention, treatment, or cure of diseases or injuries in humans and/or animals.
Ans → biological product
Explanation →
Q. A person who has already suffered from smallpox becomes immune to the disease because of ______.
Ans → Naturally acquired active immunity
Explanation →
Q. The following anticoagulant binds with Ca2+ and prevents blood clotting
Ans → Oxalate
Explanation →
Q. The inhibition of the enzyme pancreatic lipase by bile salts is overcome by a protein, namely
Ans → Colipase
Explanation →
Q. Emulsions in which the dispersed droplets are in the micron-size range.
Ans → microemulsions
Explanation →
Q. A type of kidney infection involving the glomeruli of the nephrons
Ans → glomerulonephritis
Explanation →
Q. Substance that acts as adhesives to bind together powders for making tablets (direct tableting) or granules (granulation) that are mainly used in tableting.
Ans → binder
Explanation →
Q. Cholesterol synthesis is controlled by feedback inhibition of the enzyme
Ans → HMG CoA reductase
Explanation →
Q. The representation of a compound by two or more canonical structures in which the valence electrons are rearranged to give structures of similar probability.
Ans → resonance
Explanation →
Q. reactions which proceed by means of a set of repeating cyclical steps, e.g. the free radical addition of hydrogen bromide to an alkene.
Ans → chain reaction
Explanation →
Q. Name the formation, development, and differentiation of blood cells from pluripotent hematopoietic stem cells
Ans → hematopoiesis
Explanation →
Q. The formula that shows all the atoms a molecule consist of.
Ans → molecular formula
Explanation →
Q. Procedure for estimating the concentration or biological activity of a substance by measuring its effect on a living system compared to a standard system
Ans → bioassay
Explanation →
Q. An organism that requires oxygen at levels lower than atmospheric concentration
Ans → microaerophile
Explanation →
Q. Process that occurs when the vapor pressure of the saturated aqueous solution of a substance is less than the vapor pressure of water in the ambient air.
Ans → deliquescence
Explanation →
Q. Substance that acts as adhesives to bind together powders for making tablets (direct tableting) or granules (granulation) that are mainly used in tableting.
Ans → binder
Explanation →
Q. Usually water or low-molecular-weight alcohols or compounds, used in topical applications and in wet granulation, for the production of tablets.
Ans → moistening agents
Explanation →