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An instrument used to measure the amount of rotation of plane polarized light by a compound, generally prepared in a solution
Pharmaceutical Organic Chemistry Pharmacist Competitive Exams
Q. An instrument used to measure the amount of rotation of plane polarized light by a compound, generally prepared in a solution
Ans → polarimeter
Explanation →
This question is taken from the test/quiz post: one liner| organic| B.pharmacy| Pharmacy one liners |organic chemistry| B.pharmacy file-6 - attemp/practice
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Q. An instrument used to measure the amount of rotation of plane polarized light by a compound, generally prepared in a solution
Ans → polarimeter
Explanation →
Q. A group that is used to protect a functional group from unwanted reactions. After application the protecting group can be removed to reveal the original functional group.
Ans → protecting group
Explanation →
Q. An equimolar mixture of the two enantiomeric isomers of a compound.
Ans → racemic mixture
Explanation →
Q. A a term applied to an atom or molecule having one or more free valencies.
Ans → radical
Explanation →
Q. A chemical processes in which the proportion of more electronegative substituents is decreased, or the charge is made more negative, or the oxidation number is lowered.
Ans → reduction
Explanation →
Q. The process of separation of a racemate into its two enantiomers by means of some chiral agency.
Ans → resolution
Explanation →
Q. The representation of a compound by two or more canonical structures in which the valence electrons are rearranged to give structures of similar probability.
Ans → resonance
Explanation →
Q. A process in which the forward reaction can reach an equilibrium with the reverse reaction.
Ans → reversible process
Explanation →
Q. A formal non-ambiguous, nomenclature system for the assignment of absolute configuration of structure to chiral atoms, using the Cahn, Ingold and Prelog priority rules.
Ans → R,S convention
Explanation →
Q. The term given to organic molecules which contain no multiple bonds.
Ans → saturated
Explanation →
Q. The sideways projection of a carbon-carbon single bond and the attached substituents.
Ans → sawhorse projection
Explanation →
Q. An instrument that measures the degree of absorption (or emission) of electromagnetic radiation by a substance.
Ans → spectrophotometer
Explanation →
More one-liners in - Pharmaceutical Organic Chemistry
Q. The high level of energy electrons can achieve as energy is added.
Ans → excited state
Explanation →
Q. Name an organelle of the endomembrane system that contains digestive enzymes that break down engulfed material such as foodstuffs, infectious particles, or damaged cellular components
Ans → lysosome
Explanation →
Q. Name the cell envelope structure outside the cell wall in some bacteria that allows bacteria to adhere to surfaces,
Ans → glycocalyx
Explanation →
Q. An inverse agonist is a ligand that by binding to a receptor reduces the fraction of receptors in an active conformation, thereby reducing basal activity.
Ans → Inverse Agonist
Explanation →
Q. Small sterile usually polymeric matrices, pellets, or particles for insertion or implanting into the body by surgical means or by injection to help achieve sustained release.
Ans → implants
Explanation →
Q. Hypercholesterolemia is observed in the disorder(s)
Ans → Hypothyroidism, Diabetes mellitus, Nephrotic syndrome
Explanation →
Q. Which bond is formed between the negatively charged phosphate groups that holds a lot of potential energy
Ans → high-energy phosphate bond
Explanation →
Q. Name the class of antibacterials that inhibit cell wall synthesis by binding to peptidoglycan subunits and blocking their insertion into the cell wall backbone.
Ans → glycopeptides
Explanation →
Q. Relationship between two preparations of the same drug in the same dosage form that have a similar bioavailability.
Ans → bioequivalence
Explanation →
Q. Refers to a polar molecule or portion of a molecule capable of strong attraction to water molecules
Ans → hydrophilic
Explanation →
Q. a chemical reaction in which two species (e.g. molecules, ions or radicals) react together to form new chemical species.
Ans → bimolecular reaction
Explanation →
Q. Close, tight aggregation of colloid particles, emulsion droplets, suspension particles, which are difficult to redisperse.
Ans → coagulation
Explanation →
Q. An overall reaction in which an electrophile binds to a substrate with the expulsion of another electrophile is known as
Ans → electrophilic substitution
Explanation →
Q. Name term that describes a solid of regular shape and the presence of three-dimensional order on the level of atomic dimensions, for a given molecule.
Ans → crystalline
Explanation →
Q. Used to describe when symmetric parts of a molecule are not super imposable on one another.
Ans → chirality
Explanation →
Q. The deposit of a drug in a body created by injection or by a similar mode of introduction to form a source of slow release.
Ans → depot
Explanation →
Q. Cytokines largely produced by immune system cells that help coordinate efforts against invading pathogens
Ans → interleukins
Explanation →
Q. A lymphoid cells that recognize and destroy abnormal target cells by inducing apoptosis
Ans → natural killer cells (NK cells)
Explanation →
Q. The time it takes for a decaying radioactive substance to be reduced by half.
Ans → half–life
Explanation →
Q. A thermodynamic quantity which is a measure of the degree of disorder within any system.
Ans → entropy
Explanation →
Q. The representation of a compound by two or more canonical structures in which the valence electrons are rearranged to give structures of similar probability.
Ans → resonance
Explanation →
Q. Pace at which a drug along with the stomach content leaves and enters the duodenum.
Ans → gastric emptying rate
Explanation →
Q. Name a stage in the drying of solids, above which the drying rate is linear, at which the drying rate ceases to be linear, until it reaches the equilibrium moisture content.
Ans → critical moisture content
Explanation →
Q. Class of antiprotozoan drugs long used for the treatment of malaria; interferes with heme detoxification
Ans → quinolines
Explanation →
Q. A condition in which a disease caused by or acquired during a medical procedure
Ans → iatrogenic disease
Explanation →
Q. Name leukocytes found in the peripheral blood that are characterized by numerous granules in the cytoplasm
Ans → granulocytes
Explanation →
Q. Solid material that exists at least in two different molecular arrangements, i.e., distinctly different crystal species.
Ans → polymorph
Explanation →
Q. the energy required to break a particular bond by a homolytic process.
Ans → bond energy
Explanation →
Q. A a term applied to the selective synthesis of one diastereomeric form of a compound resulting from the influence of an existing chiral centre adjacent to the developing asymmetric carbon atom.
Ans → asymmetric induction
Explanation →
Q. Name the bacteria that have more than 50% guanine and cytosine nucleotides in their DNA
Ans → high G+C gram-positive bacteria
Explanation →