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Home ❭ Questions ❭ One Liners ❭ An inverse agonist is a ligand that by binding to a receptor reduces the fraction of receptors in an active conformation, thereby reducing basal activity.
An inverse agonist is a ligand that by binding to a receptor reduces the fraction of receptors in an active conformation, thereby reducing basal activity.
Pharmacology Pharmacist Competitive Exams DSSSB Pharmacist
Q. An inverse agonist is a ligand that by binding to a receptor reduces the fraction of receptors in an active conformation, thereby reducing basal activity.
Ans → Inverse Agonist
Explanation →
This question is taken from the test/quiz post: Pharmacology Chapter 1 Revision: Key One-Liner Questions for Pharmacist Exams - attemp/practice
More oneliners in - Pharmacology Chapter 1 Revision: Key One-Liner Questions for Pharmacist Exams
Q. Continued substance use despite knowledge of having a persistent or recurrent psychological, or physical problem that is caused or exacerbated by use of the substance
Ans → Addiction
Explanation →
Q. A ligand that binds to a receptor and alters the receptor state resulting in a biological response.
Ans → Agonist
Explanation →
Q. A partial agonist is an agonist that produces a maximal response that is less than the maximal response produced by another agonist acting at the same receptors on the same tissue.
Ans → Partial Agonist
Explanation →
Q. A full agonist is an agonist that produces the largest maximal response of any known agonist that acts on the same receptor.
Ans → Full Agonist
Explanation →
Q. An inverse agonist is a ligand that by binding to a receptor reduces the fraction of receptors in an active conformation, thereby reducing basal activity.
Ans → Inverse Agonist
Explanation →
Q. The amount of change in measured output per unit change in input.
Ans → Amplification
Explanation →
Q. A drug that dulls the sense of pain. It differs from an anesthetic agent in that it relieves pain without loss of consciousness.
Ans → Analgesic
Explanation →
Q. The joint effect of two or more drugs such that the combined effect is less than the sum of the effects produced by each agent separately.
Ans → Antagonism
Explanation →
Q. The determination of the potency of a physical, chemical or biological agent, by means of a biological indicator
Ans → Biological Assay
Explanation →
Q. The percent of dose entering the systemic circulation after administration of a given dosage form.
Ans → Bioavailability
Explanation →
Q. The science and study of the ways in which the pharmaceutical formulation of administered agents can influence their pharmacodynamic and pharmacokinetic behaviour.
Ans → Biopharmaceutics
Explanation →
Q. Chemical alteration of an agent (drug) that occurs by virtue of the sojourn of the agent in a biological system.
Ans → Biotransformation
Explanation →
Q. The movement of chemicals (drugs) into, through, and out of biological organisms or their parts.
Ans → Biotranslocation
Explanation →
More one-liners in - Pharmacology
Q. The specific term used to describe carbohydrate stereoisomers differing only in configuration at the hemi-acetal carbon atom.
Ans → anomers
Explanation →
Q. Name the process producing only lactic acid as a fermentation product
Ans → homolactic fermentation
Explanation →
Q. The tendency for a molecule to acquire electrons and become reduced
Ans → redox potential
Explanation →
Q. The particular order in which electrons are arranged in an atom or molecule.
Ans → electronic configuration
Explanation →
Q. The polymers of monosaccharides or their derivatives, held together by glycosidic bonds
Ans → Polysaccharide
Explanation →
Q. A drug that dulls the sense of pain. It differs from an anesthetic agent in that it relieves pain without loss of consciousness.
Ans → Analgesic
Explanation →
Q. Inflammation of the conjunctiva in newborns caused by Neisseria gonorrhoeae transmitted during childbirth
Ans → ophthalmia neonatorum
Explanation →
Q. A common STI of the reproductive system caused by Neisseria gonorrhoeae
Ans → Gonorrheao
Explanation →
Q. A formal non-ambiguous, nomenclature system for the assignment of absolute configuration of structure to chiral atoms, using the Cahn, Ingold and Prelog priority rules.
Ans → R,S convention
Explanation →
Q. Name the adaptive immunity mediated by antibodies produced by B cells
Ans → humoral immunity
Explanation →
Q. Which is the simplest form of glycolipids which occur in the membranes of nervous tissue.
Ans → Cerebrosides
Explanation →
Q. The stage of replication during which various proteins bind to the origin of replication to begin the replication process
Ans → initiation of DNA replication
Explanation →
Q. The number of mg of KOH required to hydrolyse 1 g fat or oil is known as
Ans → Saponification number
Explanation →
Q. A full agonist is an agonist that produces the largest maximal response of any known agonist that acts on the same receptor.
Ans → Full Agonist
Explanation →
Q. Name the bacteria that have more than 50% guanine and cytosine nucleotides in their DNA
Ans → high G+C gram-positive bacteria
Explanation →
Q. Used on tablets, granules, pellets, and capsules to make them resistant to gastric fluids but designed to disintegrate, disrupt, or dissolve when the preparation enters the duodenum.
Ans → enteric coating
Explanation →
Q. Solutions (aqueous or oily), emulsions, or suspensions for rectal administration of medicaments for cleansing, diagnostic, or therapeutic purposes.
Ans → enemas
Explanation →
Q. The major dietary energy sources, besides their involvement in cell structure and various other functions is
Ans → Carbohydrates
Explanation →
Q. Small edible package made usually from gelatin or other materials that can be filled with drugs (solids or liquids) to produce a unit dose, mainly for oral use.
Ans → capsule
Explanation →
Q. Plasma lipoprotein that is inversely correlated with coronary heart disease is
Ans → HDL
Explanation →
Q. Examples of two enzymes containing zinc are
Ans → Alcohol dehydrogenase, carbonic anhydrase
Explanation →
Q. An inverse agonist is a ligand that by binding to a receptor reduces the fraction of receptors in an active conformation, thereby reducing basal activity.
Ans → Inverse Agonist
Explanation →
Q. Chemical alteration of an agent (drug) that occurs by virtue of the sojourn of the agent in a biological system.
Ans → Biotransformation
Explanation →
Q. Tablet, which does not contain a disintegrant and which is sucked to dissolve in the mouth to produce either a local (e.g., antiseptic) or systemic (e.g., vitamins) effect.
Ans → lozenge
Explanation →
Q. The two final products in the -oxidation of odd chain fatty acids are
Ans → Acetyl CoA and propionyl CoA
Explanation →