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Pharmacology

Pharmacology is the branch of medical science which deals with the mechanism, functioning, experimental analysis of impact of different drugs on living system.

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Chapters All ❱

Histamine And Antihistamine Drugs

pharmacy infoline  
30 Nov -0001   

histamine and antihistamine drugs...

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Notes All ❱

MCQs on antihistamines | medicinal chemistry | by pharmacy infoline

pharmacy infoline  
12 Jul 2021   

Antihistamines are drugs which treat rhinitis and other allergies. Typically people take antihistamines as a cheap , generic, over-the-counter medicin...

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MCQs on antihistamines | medicinal chemistry | by pharmacy infoline

pharmacy infoline  
12 Jul 2021   

Antihistamines are drugs which treat rhinitis and other allergies. Typically people take antihistamines as a cheap , generic, over-the-counter medicin...

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Commonly used drugs in Obstetric and Gynaecological conditions (starting with

prakash joshi  
5 Nov 2020   

There are some common drugs used in gynecology. Here is the list of drugs starting from "m" commonly used in obstetrics and gynecological conditio...

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Teratogenecity of drugs

solotutes  
12 Jun 2020   

Some of drugs or chemicals are fatal to embryo development. Those drugs and chemical substances which produce deviations and abnormalities in the ...

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Classification of antimicrobial drugs according to their type of action, spectrum of activity and mechanism of action

pharmacy exams  
19 May 2021   

Classification of antimicrobials is based on their type of action on microbes kill or reduce the number, spectrum of activity i.e can work on specif...

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One Liners All ❱

Pharmacist Exams revision: Pharmacology Chapter 1 - Important One Liner questions 1 of 15 〉 Continued substance use despite knowledge of having a persistent or recurrent psychological, or physical problem that is caused or exacerbated by use of the substance

Addiction

2 of 15 〉 A ligand that binds to a receptor and alters the receptor state resulting in a biological response.

Agonist

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General Pharmacology questions (one Liners)  1 of 12 〉 Adrenaline and insulin are administered through

Subcutaneous (SC) route

2 of 12 〉 In Sublingual route of drug administration Drug is absorbed through

Buccal mucosa membrane

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Revision of Pharmacology, some basic points (one liners) 1 of 12 〉 binding of Morphine and Naloxone to the Opioid receptors

competitive antagonism

2 of 12 〉 When both agonist and antagonist binds reversibly on the same site of the receptor

competitive antagonism

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Autonomic Nervous System. 1 of 3 〉 The junction of a post-ga1nglionic axonal terminal with its effector cell is termed a neuroeffector junction.

Neuroeffector junction

2 of 3 〉 Nerves that convey impulses from the brain and spinal cord (CNS) to muscles, glands and other effector organs

Efferent (Motor)

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TYPES OF CANCER 1 of 7 〉 cancer derived from germ cell which are commonly found in the brain of young ages.

Germinoma

2 of 7 〉 cancer of skin that develops when melanocytes (the cells that give the skin its tan or brown color) start to grow out of control.

Melanoma

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Hospital and Clinical Pharmacy Important Questions (one liners) 1 of 9 〉 Griseofulvin is better absorbed in

Presence of fatty meal

2 of 9 〉 Death due to cyanide poisoning results from

Inhibition of cytochrome oxidase

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Practice (MCQs) All ❱

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Question 1 of 56

Q.1 Compared to subcutaneous injection, the intramus- cular injection of drugs:

  • Is more painful
  • Produces faster response
  • Is unsuitable for depot preparations
  • Carries greater risk of anaphylactic reaction

Question 2 of 56

Q.2 The majority of drugs cross biological membranes primarily by

  • Passive diffusion
  • Facilitated diffusion
  • Active transport
  • Pinocytosis

Question 3 of 56

Q.3 Which of the following drugs is most likely to be absorbed from the stomach

  • Hyoscine hydrobromide
  • Morphine sulfate
  • Diclofenac sodium
  • Quinine dihydrochloride

Question 4 of 56

Q.4 The most important factor governing absorption of a drug from intact skin is

  • Nature of the base used in the formulation
  • Lipid solubility of the drug
  • Molecular weight of the drug
  • Site of application

Question 5 of 56

Q.5 Bioavailability differences among oral formulations of a drug are most likely to occur if the drug

  • Undergoes little first-pass metabolism
  • Is incompletely absorbed
  • Is freely water soluble
  • Is completely absorbed

Question 6 of 56

Q.6 Marked redistribution is a feature of

  • Highly plasma protein bound drugs
  • Depot preparations
  • Highly lipid soluble drugs
  • Poorly lipid soluble drugs

Question 7 of 56

Q.7 High plasma protein binding

  • Increases volume of distribution of the drug
  • Generally makes the drug long acting
  • Facilitates glomerular filtration of the drug
  • Minimises drug interactions

Question 8 of 56

Q.8 Which of the following is a prodrug

  • Enalapril
  • Menapril
  • Thiazine
  • Penicillin

Question 9 of 56

Q.9 Microsomal enzyme induction can be a cause of

  • Tolerance
  • Physical dependence
  • Psychological dependence
  • Idiosyncrasy

Question 10 of 56

Q.10 Glomerular filtration of a drug is affected by its

  • Plasma protein binding
  • Lipid solubility
  • Degree of ionization
  • Rate of tubular secretion

Question 11 of 56

Q.1 Which of the following organs is innervated only by parasympathetic nerves

  • Sweat glands
  • Ciliary muscle
  • Iris muscles
  • Splenic capsule

Question 12 of 56

Q.2 The following cotransmitter is most probably involved in mediating nonadrenergic-noncholinergic (NANC) relaxation of the gut

  • Nitric oxide (NO)
  • Adenosine
  • Neuropeptide Y (NPY)
  • Kallidin

Question 13 of 56

Q.3 The major postjunctional cholinergic receptor is of the muscarinic type at the following site

  • Neuromuscular junction
  • Postganglionic parasympathetic
  • Adrenal medulla
  • Autonomic ganglia

Question 14 of 56

Q.4 The choline ester resistant to both true and pseudo- cholinesterase is

  • Bethanechol
  • Butyrylcholine
  • Methacholine
  • Benzoylcholine

Question 15 of 56

Q.5 The smooth muscle structure that is relaxed by choli- nergic drugs is

  • Colon
  • Gastric fundus
  • Bladder trigone
  • Major bronchi

Question 16 of 56

Q.6 Pilocarpine is used for

  • Glaucoma
  • Paralytic ileus
  • Urinary retention
  • Infection

Question 17 of 56

Q.7 The following inhibitor binds only to the ani-onic site of the cholinesterase enzyme

  • Neostigmine
  • Edrophonium
  • Physostigmine
  • Dyflos

Question 18 of 56

Q.8 Reactivation of cholinesterase enzyme occurs on hydrolysis of the inhibitor by the same enzyme mole- cule in case of the following anticholinesterase

  • Edrophonium
  • Dyflos
  • Tacrine
  • Neostigmine

Question 19 of 56

Q.9 Pyridostigmine differs from neostigmine in that

  • It produces less muscarinic side effects
  • It is more potent orally
  • It is longer acting
  • It does not have any direct action on NM receptor

Question 20 of 56

Q.10 The site of action of miotics for therapeutic effect in angle closure glaucoma is

  • Canal of Schlemm
  • Ciliary body
  • Ciliary muscle
  • Sphincter pupillae muscle

Question 21 of 56

Q.1 Labetalol differs from propranolol in that

  • It has additional α1 blocking property
  • It is a selective βS1 blocker
  • It does not undergo first pass metabolism
  • All of the above

Question 22 of 56

Q.2 Select the β-adrenergic blocker that has additional β1blocking, vasodilator and antioxidant properties

  • Celiprolol
  • Metoprolol
  • Carvedilol
  • Acebutolol

Question 23 of 56

Q.3 Select the β adrenergic blocker that is primarily eliminated unchanged by renal excretion

  • Atenolol
  • Carbinol
  • Ethanol
  • Dompirol

Question 24 of 56

Q.4 Select the ultrashort acting cardioselective β adre- nergic blocker

  • Carbinol
  • Ethanol
  • Esmolol
  • Propalol

Question 25 of 56

Q.5 The following disease is worsened by propranolol

  • Raynaud’s disease
  • Infection
  • Heart attack
  • Epilepsy

Question 26 of 56

Q.6 Select the drug which is administered orally for erectile dysfunction in men

  • Albendazole
  • Mebendazole
  • Cocaine
  • Sildenafil

Question 27 of 56

Q.7 Which of the following is a selective α1A receptor bloc- ker that affords symptomatic relief in benign prostatic hypertrophy without producing significant fall in blood pressure

  • Doxazosin
  • Alprostadil
  • Tamsulosin
  • Yohimbine

Question 28 of 56

Q.8 The bladder trigone and prostatic muscles are relaxed by

  • Adrenergic α1 agonists
  • Adrenergic α1 antagonists
  • Adrenergic α2 antagonists
  • Adrenergic α2 agonists

Question 29 of 56

Q.9 The drug which produces vasoconstriction despite being an α adrenergic blocker is

  • Tolazoline
  • Desmopressin
  • Ergotamine
  • Sildenafil

Question 30 of 56

Q.10 While undergoing a surgical procedure a patient deve- lops hypotension. Which drug can be injected intramuscularly to raise his BP

  • Noradrenaline
  • Mephentermine
  • Isoxsuprine
  • Oxymetazoline

Question 31 of 56

Q.1 Labetalol differs from propranolol in that

  • It has additional α1 blocking property
  • It is a selective βS1 blocker
  • It does not undergo first pass metabolism
  • All of the above

Question 32 of 56

Q.2 Select the β-adrenergic blocker that has additional β1blocking, vasodilator and antioxidant properties

  • Celiprolol
  • Metoprolol
  • Carvedilol
  • Acebutolol

Question 33 of 56

Q.3 Select the β adrenergic blocker that is primarily eliminated unchanged by renal excretion

  • Atenolol
  • Carbinol
  • Ethanol
  • Dompirol

Question 34 of 56

Q.4 Select the ultrashort acting cardioselective β adre- nergic blocker

  • Carbinol
  • Ethanol
  • Esmolol
  • Propalol

Question 35 of 56

Q.5 The following disease is worsened by propranolol

  • Raynaud’s disease
  • Infection
  • Heart attack
  • Epilepsy

Question 36 of 56

Q.6 Select the drug which is administered orally for erectile dysfunction in men

  • Albendazole
  • Mebendazole
  • Cocaine
  • Sildenafil

Question 37 of 56

Q.7 Which of the following is a selective α1A receptor bloc- ker that affords symptomatic relief in benign prostatic hypertrophy without producing significant fall in blood pressure

  • Doxazosin
  • Alprostadil
  • Tamsulosin
  • Yohimbine

Question 38 of 56

Q.8 The bladder trigone and prostatic muscles are relaxed by

  • Adrenergic α1 agonists
  • Adrenergic α1 antagonists
  • Adrenergic α2 antagonists
  • Adrenergic α2 agonists

Question 39 of 56

Q.9 The drug which produces vasoconstriction despite being an α adrenergic blocker is

  • Tolazoline
  • Desmopressin
  • Ergotamine
  • Sildenafil

Question 40 of 56

Q.10 While undergoing a surgical procedure a patient deve- lops hypotension. Which drug can be injected intramuscularly to raise his BP

  • Noradrenaline
  • Mephentermine
  • Isoxsuprine
  • Oxymetazoline

Question 41 of 56

Q.1 Labetalol differs from propranolol in that

  • It has additional α1 blocking property
  • It is a selective βS1 blocker
  • It does not undergo first pass metabolism
  • All of the above

Question 42 of 56

Q.2 Select the β-adrenergic blocker that has additional β1blocking, vasodilator and antioxidant properties

  • Celiprolol
  • Metoprolol
  • Carvedilol
  • Acebutolol

Question 43 of 56

Q.3 Select the β adrenergic blocker that is primarily eliminated unchanged by renal excretion

  • Atenolol
  • Carbinol
  • Ethanol
  • Dompirol

Question 44 of 56

Q.4 Select the ultrashort acting cardioselective β adre- nergic blocker

  • Carbinol
  • Ethanol
  • Esmolol
  • Propalol

Question 45 of 56

Q.5 The following disease is worsened by propranolol

  • Raynaud’s disease
  • Infection
  • Heart attack
  • Epilepsy

Question 46 of 56

Q.6 Select the drug which is administered orally for erectile dysfunction in men

  • Albendazole
  • Mebendazole
  • Cocaine
  • Sildenafil

Question 47 of 56

Q.7 Which of the following is a selective α1A receptor bloc- ker that affords symptomatic relief in benign prostatic hypertrophy without producing significant fall in blood pressure

  • Doxazosin
  • Alprostadil
  • Tamsulosin
  • Yohimbine

Question 48 of 56

Q.8 The bladder trigone and prostatic muscles are relaxed by

  • Adrenergic α1 agonists
  • Adrenergic α1 antagonists
  • Adrenergic α2 antagonists
  • Adrenergic α2 agonists

Question 49 of 56

Q.9 The drug which produces vasoconstriction despite being an α adrenergic blocker is

  • Tolazoline
  • Desmopressin
  • Ergotamine
  • Sildenafil

Question 50 of 56

Q.10 While undergoing a surgical procedure a patient deve- lops hypotension. Which drug can be injected intramuscularly to raise his BP

  • Noradrenaline
  • Mephentermine
  • Isoxsuprine
  • Oxymetazoline

Question 51 of 56

Q.1 The following are excreted faster in basicurine

  • Weak acids
  • Strong acids
  • Weak Bases
  • None of the above

Question 52 of 56

Q.2 A good example of chemical antagonism

  • Heparin & Protamine
  • Protamine & Zinc
  • Heparin & Prothrombin
  • All the above

Question 53 of 56

Q.3 Active transport differs from facilitated transport in following ways, except

  • Carrier is involved
  • It is against concentration gradient
  • Energy is required
  • All of the above

Question 54 of 56

Q.4 Acidic drugs mainly bind to plasma

  • Albumin
  • acid glycoprotein
  • Weak acids
  • Heparin & Protamine

Question 55 of 56

Q.5 _______ is expressed in both the intestinal epithelium and the kidney.

  • CYP378A
  • CYP4B2
  • CYP3A4
  • CYP256

Question 56 of 56

Q.6 N-oxidation will be involved with the metabolism of following drugs, except

  • Dapsone
  • Meperidine
  • Phenytoin
  • Chlorpheniramine

Practice Tests All ❱

Pharmacology and Toxicology MCQs | Practice Test #1

Pharmacology and Toxicology MCQs | Practice Test #1
(20 Questions , 186 attempts)

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Classification of drugs in pharmacology Aptitude Test

Classification of drugs in pharmacology Aptitude Test
(30 Questions , 597 attempts)

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Pharmacology Aptitude Test

Pharmacology Aptitude Test
(10 Questions , 536 attempts)

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Test on Drugs classifications 1

Test on Drugs classifications 1
(11 Questions , 159 attempts)

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Online Practice Test for Pharmacy exams, previous Year questions

Online Practice Test for Pharmacy exams, previous Year questions
(50 Questions , 2696 attempts)

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