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The enzyme defect in acute intermittent porphyria
Biochemistry Pharmacist Competitive Exams
Q. The enzyme defect in acute intermittent porphyria
Ans → Uroporphyrinogen synthase I
Explanation →
This question is taken from the test/quiz post: Biochemistry Important One Liners Questions On HEMOGLOBIN AND PORPHYRINS - attemp/practice
More oneliners in - Biochemistry Important One Liners Questions On HEMOGLOBIN AND PORPHYRINS
Q. The oxidation of ferrous (Fe2+) iron to ferric (Fe3+) iron in hemoglobin results in the formation of a compound namely
Ans → Methemoglobin
Explanation →
Q. Name the compound that is increased in RBC of anemic patients to facilitate the supply of O2 to the tissues
Ans → 2,3-Bisphosphoglycerate
Explanation →
Q. Sickling of RBC in sickle-cell anemia is due to polymerization of
Ans → Deoxyhemoglobin,
Explanation →
Q. The disorders characterized by decreased synthesis or total absence of globin chains of hemoglobin are collectively known as
Ans → Thalassemias
Explanation →
Q. The intermediate of citric acid cycle that is involved in heme synthesis
Ans → Succinyl CoA
Explanation →
Q. The enzyme defect in acute intermittent porphyria
Ans → Uroporphyrinogen synthase I
Explanation →
Q. The enzyme that is regulated by feedback inhibition in heme synthesis is
Ans → δ -Aminolevulinate synthase
Explanation →
Q. The compound that facilitates the release of O2 from oxyhemoglobin
Ans → C1– , H+ , 2, 3-BPG
Explanation →
Q. Name the amino acid that directly participates in the synthesis of heme
Ans → Glycine
Explanation →
More one-liners in - Biochemistry
Q. An agent able to produce positively charged hydrogen ions (H+). [Since the hydrogen ion is a bare proton, it usually exists in a solvated form (such as H3O+).]
Ans → acid
Explanation →
Q. The copper containing protein involved for the conversion of ferrous iron (Fe2+) to ferric iron (Fe3+) in the plasma
Ans → Ceruloplasmin
Explanation →
Q. The extrinsic and intrinsic pathways result in the formation of a common activated factor
Ans → Staurt factor
Explanation →
Q. The power of a microscope (or lens) to produce an image that appears larger than the actual specimen, expressed as a factor of the actual size
Ans → magnification
Explanation →
Q. Name the capillary bed in the nephron of the kidney that filters blood to form urine
Ans → glomerulus
Explanation →
Q. An enzyme of purine metabolism associated with immunodeficiency disease
Ans → Adenosine deaminase
Explanation →
Q. A conformation in which substituents on two attached saturated carbon atoms overlap when viewed as a Newman projection.
Ans → eclipsed
Explanation →
Q. Refers to a nonpolar molecule or portion of a molecule not capable of strong attraction to water molecules
Ans → hydrophobic
Explanation →
Q. When a reaction provides the agents for a subsequent reaction.
Ans → chain reaction
Explanation →
Q. The enzyme defect in acute intermittent porphyria
Ans → Uroporphyrinogen synthase I
Explanation →
Q. the angle between groups attached on adjacent carbon atoms when viewed in a Newman projection.
Ans → dihedral angle
Explanation →
Q. Molecules that exist only during a chemical reaction; not before or after the reaction.
Ans → intermediate
Explanation →
Q. The metabolic pathway concerned with the conversion of L-xylulose to D-xylulose is
Ans → Uronic acid pathway
Explanation →
Q. A process in which the forward reaction can reach an equilibrium with the reverse reaction.
Ans → reversible process
Explanation →
Q. The lipoproteins synthesized in the intestinal mucosal cells from the absorbed lipids are
Ans → Chylomicrons
Explanation →
Q. Carbohydrates are the polyhydroxyaldehydes or ketones, or compounds which produce them on
Ans → Hydrolysis
Explanation →
Q. On a light microscope, the lenses closest to the specimen, typically located at the ends of turrets is called as
Ans → objective lenses
Explanation →
Q. The disease characterized by impairment in the absorption of neutral amino acids
Ans → Hartnup’s disease
Explanation →
Q. Type of comparative bioavailability study designed in such a way as to take into account differences in bioavailability arising from differences between patients suffering from disease
Ans → crossover study
Explanation →
Q. Adherence of particles into a larger mass due to moisture, static charge, or chemical or mechanical binding
Ans → agglomeration
Explanation →
Q. The lipids that are not the structural components of biological membranes
Ans → Triacylglycerols
Explanation →
Q. The copper containing protein involved for the conversion of ferrous iron (Fe2+) to ferric iron (Fe3+) in the plasma
Ans → Ceruloplasmin
Explanation →
Q. The carbohydrate that is taken as a reference for writing the configuration of others
Ans → Glyceraldehydes
Explanation →
Q. Acetyl CoA from the mitochondria is transported into the cytosol after its conversion to
Ans → Citrate
Explanation →