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A technique that uses a fluorescence microscope and antibody-specific fluorochromes to determine the presence of specific pathogens in a specimen
Microbiology Pharmacist Competitive Exams
Q. A technique that uses a fluorescence microscope and antibody-specific fluorochromes to determine the presence of specific pathogens in a specimen
Ans → immunofluorescence
Explanation →
This question is taken from the test/quiz post: Microbiology Important questions (one liners Set - 7) Pharmacy - attemp/practice
More oneliners in - Microbiology Important questions (one liners Set - 7) Pharmacy
Q. Name the process producing a mixture of lactic acid, ethanol and/or acetic acid, and CO2 as fermentation products
Ans → heterolactic fermentation
Explanation →
Q. Name the organism that uses fixed organic carbon compounds as its carbon source
Ans → heterotroph
Explanation →
Q. Name the bacteria that have more than 50% guanine and cytosine nucleotides in their DNA
Ans → high G+C gram-positive bacteria
Explanation →
Q. Which bond is formed between the negatively charged phosphate groups that holds a lot of potential energy
Ans → high-energy phosphate bond
Explanation →
Q. Name the large group of antigens bound by antibodies; large enough to settle out of fluid suspension
Ans → immune complex
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Q. A staining technique in which cells are fixed and holes dissolved in the membrane to allow passage of labeled antibodies to bind specific intracellular targets
Ans → immunocytochemistry (ICC)
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Q. Technique in which antibody or antigen can be concentrated by passing fluids through porous membranes, and target molecules are captured as they pass
Ans → immunofiltration
Explanation →
Q. Fungal disease caused by the dimorphic fungus Histoplasma capsulatum
Ans → histoplasmosis
Explanation →
Q. A technique that uses a fluorescence microscope and antibody-specific fluorochromes to determine the presence of specific pathogens in a specimen
Ans → immunofluorescence
Explanation →
Q. A staining technique in which labeled antibodies are bound to specific cells in a tissue section
Ans → immunohistochemistry (IHC)
Explanation →
Q. DNA-binding proteins found in eukaryotes and archaea that aid in orderly packaging of chromosomal DNA
Ans → histones
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Q. Outside the organism in a test tube or artificial environment is known as
Ans → in vitro
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Q. Proinflammatory molecule released by basophils and mast cells in response to stimulation by other cytokines and chemical mediators
Ans → histamine
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Q. This refers to protozoans that consume food particles through phagoctytosis
Ans → holozoic
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Q. Name the process producing only lactic acid as a fermentation product
Ans → homolactic fermentation
Explanation →
Q. Vaccine composed of whole pathogen cells or viruses that have been killed or inactivated through treatment with heat, radiation, or chemicals
Ans → inactivated vaccine
Explanation →
Q. Name the retrovirus responsible for acquired immune deficiency syndrome (AIDS) in humans
Ans → human immunodeficiency virus (HIV)
Explanation →
Q. The number of individuals with new infections of a particular disease in a given period of time is called
Ans → incidence
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Q. Movement of a pathogen from one host to another population through physical contact or through droplet transmission
Ans → horizontal direct transmission
Explanation →
Q. Inflammation of the conjunctiva in newborns caused by Chlamydia trachomatis transmitted during childbirth is
Ans → inclusion conjunctivitis
Explanation →
Q. Name the prokaryotic cell cytoplasmic structures for storing specific nutrients and other resources needed by cells
Ans → inclusions
Explanation →
Q. Introduction of genetic material from one organism to another organism within the same generation
Ans → horizontal gene transfer
Explanation →
Q. The first stage of acute disease, during which the pathogen begins multiplying in the host and signs and symptoms are not observable
Ans → incubation period
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Q. The successful colonization of a microorganism within a host is called as
Ans → infection
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Q. Name the types of host cells that a particular virus is able to infect
Ans → host range
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Q. Highly contagious and acute viral disease of the respiratory tract caused by the influenza virus
Ans → influenza
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Q. Serious infection caused by Trypanosoma brucei and spread by the bite of the tsetse fly
Ans → human African trypanosomiasis
Explanation →
Q. Proteins that participate in ribosome assembly during initiation
Ans → initiation factors
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Q. A group of common sexually transmitted viruses that may be associated with genital warts or with cervical cancer
Ans → human papillomavirus (HPV)
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Q. Name the adaptive immunity mediated by antibodies produced by B cells
Ans → humoral immunity
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Q. Name the enzyme produced by pathogens that degrades hyaluronic acid between adjacent cells in connective tissue
Ans → hyaluronidase
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Q. The stage of replication during which various proteins bind to the origin of replication to begin the replication process
Ans → initiation of DNA replication
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Q. The stage of transcription during which RNA polymerase binds to a promoter and transcription begins
Ans → initiation of transcription
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Q. The the joining of two complementary single-stranded DNA molecules
Ans → hybridization
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Q. Small number of cells added to medium to start a culture is commonly called
Ans → inoculum
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Q. Type of mutation involving the addition of one or more bases into a DNA sequence
Ans → insertion
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Q. The clones of cell produced by fusing a normal B cell with a myeloma cell that is capable of producing monoclonal antibodies indefinitely
Ans → hybridoma
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Q. Refers to a polar molecule or portion of a molecule capable of strong attraction to water molecules
Ans → hydrophilic
Explanation →
Q. Cytokines largely produced by immune system cells that help coordinate efforts against invading pathogens
Ans → interleukins
Explanation →
Q. Refers to a nonpolar molecule or portion of a molecule not capable of strong attraction to water molecules
Ans → hydrophobic
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Q. A host in which a parasite goes through some stages of its life cycle before migrating to the definitive host
Ans → intermediate host
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Q. Potentially damaging immune response against an antigen is called
Ans → hypersensitivity
Explanation →
More one-liners in - Microbiology
Q. An antibacterial and antiprotozoan drug of the nitroimidazole class that is activated in anaerobic target cell and introduces DNA strand breakage, thus interfering with DNA replication in target cells
Ans → metronidazole
Explanation →
Q. A polymer assembled from of individual units, monomers, that bind together like building blocks
Ans → macromolecule
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Q. Greasy, semi-solid preparation for external application, often anhydrous, containing dissolved or dispersed medicaments.
Ans → ointment
Explanation →
Q. The inflammation of the gums that is more severe than gingivitis, spreading deeper into the tissues
Ans → periodontitis
Explanation →
Q. A simple spherical arrangement of amphipathic lipid molecules with nonpolar tails aggregated within the interior and polar heads forming the outer surface
Ans → micelle
Explanation →
Q. Process of agglomeration that converts fine powders or granules of bulk drugs and excipients into small, free-flowing, spherical, or semi-spherical units, referred to as pellets.
Ans → pelletization
Explanation →
Q. An instrument used to measure the amount of rotation of plane polarized light by a compound, generally prepared in a solution
Ans → polarimeter
Explanation →
Q. Name a dormant cell that survives in the death phase and is resistant to most antibiotics
Ans → persister
Explanation →
Q. the energy required to break a particular bond by a homolytic process.
Ans → bond energy
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Q. This refers to a cytokine signal released from a cell to a receptor on a nearby cell
Ans → paracrine function
Explanation →
Q. A form of microbial control using heat that is applied to foods; kills pathogens and reduces the number of spoilage-causing microbes while maintaining food quality
Ans → pasteurization
Explanation →
Q. A type of inclusion containing volutin, a polymerized inorganic phosphate that appears red when stained with methylene blue
Ans → metachromatic granule
Explanation →
Q. Name the term that refers to a nonpolar molecule or portion of a molecule not capable of strong attraction to water molecules
Ans → hydrophobic
Explanation →
Q. Which enzymes in glycolysis catalyses an irreversible reaction
Ans → Pyruvate kinase , Phosphofructokinase, Hexokinase
Explanation →
Q. When parts of the nucleus of atoms are forced together to create a new one.
Ans → nuclear fusion
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Q. The chemical reaction that removes electrons (often as part of H atoms) from donor molecules, leaving them oxidized
Ans → oxidation reaction
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Q. DNA sequence located between the promoter region and the first coding gene to which a repressor protein can bind
Ans → operator
Explanation →
Q. The cofactor required for the conversion of phenylalanine to tyrosine is
Ans → Tetrahydrobiopterin
Explanation →
Q. Name the process in which rapid freezing, followed by placement under a vacuum, of a material so that water is lost by sublimation, thereby inhibiting microbial growth
Ans → lyophilization
Explanation →
Q. Emulsions in which the dispersed droplets are in the micron-size range.
Ans → microemulsions
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Q. The process of separation of a racemate into its two enantiomers by means of some chiral agency.
Ans → resolution
Explanation →
Q. The isolation of an individual for the purpose of preventing the spread of disease
Ans → quarantine
Explanation →
Q. The enzyme defect in acute intermittent porphyria
Ans → Uroporphyrinogen synthase I
Explanation →
Q. A conformation in which substituents on two attached saturated carbon atoms overlap when viewed as a Newman projection.
Ans → eclipsed
Explanation →
Q. Round or oval bodies as they lack cell wall. So shape is not fixed.
Ans → Mycoplasmas
Explanation →
Q. Transport of glucose from the lumen to the intestinal mucosal cells is coupled with diffusion of
Ans → Enteropeptidase
Explanation →
Q. The lipids that possess both hydrophobic (non -polar) and hydrophilic (polar) groups are known as
Ans → amphipathic
Explanation →
Q. A staining technique in which labeled antibodies are bound to specific cells in a tissue section
Ans → immunohistochemistry (IHC)
Explanation →
Q. Name the class of T cells that is the central orchestrator of the cellular and humoral defenses of adaptive immunity and the cellular defenses of innate immunity
Ans → helper T cells
Explanation →
Q. Refers to a polar molecule or portion of a molecule capable of strong attraction to water molecules
Ans → hydrophilic
Explanation →