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Home ❭ Questions ❭ One Liners ❭ Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve extended release.
Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve extended release.
Pharmaceutics Pharmacist Competitive Exams
Q. Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve extended release.
Ans → matrix formulation
Explanation →
This question is taken from the test/quiz post: one liners Pharmaceutics| B.Pharmacy| Pharmacy file-5 - attemp/practice
More oneliners in - one liners Pharmaceutics| B.Pharmacy| Pharmacy file-5
Q. Insertion or grafting of a biological, living, inert, or radioactive material into the body.
Ans → implantation
Explanation →
Q. Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve extended release.
Ans → matrix formulation
Explanation →
Q. Small sterile usually polymeric matrices, pellets, or particles for insertion or implanting into the body by surgical means or by injection to help achieve sustained release.
Ans → implants
Explanation →
Q. Emulsions in which the dispersed droplets are in the micron-size range.
Ans → microemulsions
Explanation →
Q. Number that expresses the reduction in the numbers of a microorganism, brought about by a sterilizaion process.
Ans → inactivation factor (IF)
Explanation →
Q. Reversible formation of association colloids from surfactants in nonpolar solvents leads to aggregates termed inverted (or inverse, reverse, or reversed) micelles.
Ans → inverted micelle
Explanation →
Q. A Solid spherical particles of micron-size range, used as matrix dosage forms.
Ans → microsphere
Explanation →
Q. Artificial spherical lipid bilayer droplet formed mainly from phospholipids having a core of water phase, small enough to form a relatively stable dispersion in aqueous media and with potential use in drug delivery.
Ans → liposome
Explanation →
Q. Concentration of a drug that must be achieved in the plasma before any desired therapeutic or pharmacological effect can be obtained.
Ans → minimum effective plasma concentration
Explanation →
Q. Initial, typically larger than the maintenance dose of a drug given to a patient at the start of pharmacotherapy.
Ans → loading dose
Explanation →
Q. Lowest concentration of an antibacterial drug necessary to inhibit the growth of a microorganism.
Ans → minimum inhibitory concentration (MIC)
Explanation →
Q. Tablet, which does not contain a disintegrant and which is sucked to dissolve in the mouth to produce either a local (e.g., antiseptic) or systemic (e.g., vitamins) effect.
Ans → lozenge
Explanation →
Q. Release of a drug from a dosage form that it is not immediate
Ans → modified release
Explanation →
More one-liners in - Pharmaceutics
Q. The energy levels of electrons in an atom which may be described in terms of the four quantum numbers.
Ans → atomic orbital
Explanation →
Q. Molecules that contain groups with characteristically different properties, e.g., both hydrophilic and lipophilic (hydrophobic) properties.
Ans → amphiphilic
Explanation →
Q. Dosage form in which the active ingredient is insoluble in the carrier; includes aerosols, suspensions, emulsions , and foams
Ans → disperse system
Explanation →
Q. Solid material that exists at least in two different molecular arrangements, i.e., distinctly different crystal species.
Ans → polymorph
Explanation →
Q. Tablet, which does not contain a disintegrant and which is sucked to dissolve in the mouth to produce either a local (e.g., antiseptic) or systemic (e.g., vitamins) effect.
Ans → lozenge
Explanation →
Q. Name the organism that uses fixed organic carbon compounds as its carbon source
Ans → heterotroph
Explanation →
Q. Science of preparation of drugs, dosage forms, and drug delivery systems taking into account the pharmacokinetics and pharmacodynamics of the drug as well as its physical and chemical properties.
Ans → pharmaceutics
Explanation →
Q. a substance that, when added to a reaction mixture, changes (speeds up) the rate of attainment of equilibrum in the system without itself undergoing a permanent chemical change.
Ans → catalyst
Explanation →
Q. Reversible formation of association colloids from surfactants in nonpolar solvents leads to aggregates termed inverted (or inverse, reverse, or reversed) micelles.
Ans → inverted micelle
Explanation →
Q. The compound implicated in the development of cataract in diabetic patients is
Ans → Sorbitol
Explanation →
Q. The deposit of a drug in a body created by injection or by a similar mode of introduction to form a source of slow release.
Ans → depot
Explanation →
Q. Usually water or low-molecular-weight alcohols or compounds, used in topical applications and in wet granulation, for the production of tablets.
Ans → moistening agents
Explanation →
Q. A formal non-ambiguous, nomenclature system for the assignment of absolute configuration of structure to chiral atoms, using the Cahn, Ingold and Prelog priority rules.
Ans → R,S convention
Explanation →
Q. Growth on the skin associated with infection by any of the human papilloma viruses (HPV); commonly known as a wart
Ans → papilloma
Explanation →
Q. Antihelminthic drug of the benzimidazole class that binds to helminthic β-tubulin, preventing microtubule formation
Ans → mebendazole
Explanation →
Q. Reversal of coagulation or flocculation, i.e., the dispersion of aggregates to form a stable colloidal suspension or emulsion.
Ans → deflocculation
Explanation →
Q. Cellulose is not digested in humans due to lack of the enzyme that hydrolyses
Ans → β-Glycosidic bonds
Explanation →
Q. Name the organism that depends on high concentrations of salt in the environment to grow
Ans → halophile
Explanation →
Q. Name the antiviral drugs that block the activity of the HIV integrase responsible for recombination of a DNA copy of the viral genome into the host cell chromosome
Ans → integrase inhibitors
Explanation →
Q. The amino acid that is completely destroyed by acid hydrolysis of protein
Ans → Tryptophan
Explanation →
Q. The bonds in protein structure that are not broken on denaturation.
Ans → Peptide bonds
Explanation →
Q. Antibody monomer involved in defense against parasites and allergic reactions
Ans → IgE
Explanation →
Q. Name the enzyme produced by pathogens that degrades hyaluronic acid between adjacent cells in connective tissue
Ans → hyaluronidase
Explanation →
Q. Muscular contractions of the gastrointestinal tract that propel ingested material through the stomach,
Ans → peristalsis
Explanation →