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Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve extended release.
Pharmaceutics Pharmacist Competitive Exams
Q. Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve extended release.
Ans → matrix formulation
Explanation →
This question is taken from the test/quiz post: one liners Pharmaceutics| B.Pharmacy| Pharmacy file-5 - attemp/practice
More oneliners in - one liners Pharmaceutics| B.Pharmacy| Pharmacy file-5
Q. Insertion or grafting of a biological, living, inert, or radioactive material into the body.
Ans → implantation
Explanation →
Q. Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve extended release.
Ans → matrix formulation
Explanation →
Q. Small sterile usually polymeric matrices, pellets, or particles for insertion or implanting into the body by surgical means or by injection to help achieve sustained release.
Ans → implants
Explanation →
Q. Emulsions in which the dispersed droplets are in the micron-size range.
Ans → microemulsions
Explanation →
Q. Number that expresses the reduction in the numbers of a microorganism, brought about by a sterilizaion process.
Ans → inactivation factor (IF)
Explanation →
Q. Reversible formation of association colloids from surfactants in nonpolar solvents leads to aggregates termed inverted (or inverse, reverse, or reversed) micelles.
Ans → inverted micelle
Explanation →
Q. A Solid spherical particles of micron-size range, used as matrix dosage forms.
Ans → microsphere
Explanation →
Q. Artificial spherical lipid bilayer droplet formed mainly from phospholipids having a core of water phase, small enough to form a relatively stable dispersion in aqueous media and with potential use in drug delivery.
Ans → liposome
Explanation →
Q. Concentration of a drug that must be achieved in the plasma before any desired therapeutic or pharmacological effect can be obtained.
Ans → minimum effective plasma concentration
Explanation →
Q. Initial, typically larger than the maintenance dose of a drug given to a patient at the start of pharmacotherapy.
Ans → loading dose
Explanation →
Q. Lowest concentration of an antibacterial drug necessary to inhibit the growth of a microorganism.
Ans → minimum inhibitory concentration (MIC)
Explanation →
Q. Tablet, which does not contain a disintegrant and which is sucked to dissolve in the mouth to produce either a local (e.g., antiseptic) or systemic (e.g., vitamins) effect.
Ans → lozenge
Explanation →
Q. Release of a drug from a dosage form that it is not immediate
Ans → modified release
Explanation →
More one-liners in - Pharmaceutics
Q. The Threshold detergent concentration at which micelle formation begins in the bulk phase is called
Ans → critical micelle concentration (cmc)
Explanation →
Q. Name a toxin that affects cell membrane function by either forming pores or disrupting the phospholipid bilayer
Ans → membrane-disrupting toxin
Explanation →
Q. Technological process consisting of the application of a substance, which forms a layer e.g, to protect the drug
Ans → coating
Explanation →
Q. Plasma albumin performs the following functions
Ans → Osmotic, Transport , Nutritive
Explanation →
Q. Pace at which a drug along with the stomach content leaves and enters the duodenum.
Ans → gastric emptying rate
Explanation →
Q. Salivary -amylase becomes inactive in the stomach primarily due to
Ans → Inactivation by low pH
Explanation →
Q. Part of the orbital area in an atom where it is impossible to find an electron.
Ans → node
Explanation →
Q. The amino acid required for the formation of glutathione
Ans → Glycine, Cysteine, Glutamate
Explanation →
Q. A common STI of the reproductive system caused by Neisseria gonorrhoeae
Ans → Gonorrheao
Explanation →
Q. Vehicle often ethanol used in combination to increase the solubility of drugs.
Ans → cosolvent
Explanation →
Q. A a variant of PCR involving the use of fluorescence to allow for the monitoring of the increase in double-stranded template during a PCR reaction as it occurs
Ans → real-time PCR
Explanation →
Q. Potentially damaging immune response against an antigen is called
Ans → hypersensitivity
Explanation →
Q. For a substance, the time required for the amount of a drug or a substance in a biological system to be reduced to one-half of its value by biological processes when the rate of removal is approximately exponential.
Ans → biological half life
Explanation →
Q. A type of inclusion containing volutin, a polymerized inorganic phosphate that appears red when stained with methylene blue
Ans → metachromatic granule
Explanation →
Q. Repair of the sugar-phosphate backbone of the DNA, making the DNA molecule continuous
Ans → ligation
Explanation →
Q. Which is the simplest form of glycolipids which occur in the membranes of nervous tissue.
Ans → Cerebrosides
Explanation →
Q. Name the enzyme associated with hyperuricemia
Ans → PRPP synthetase, HGPRT , Glucose 6-phosphatase
Explanation →
Q. Name the amino acid that directly participates in the synthesis of heme
Ans → Glycine
Explanation →
Q. the phenomenon in which plane polarised light is turned in a clockwise direction.
Ans → dextrorotatory
Explanation →
Q. Outside the organism in a test tube or artificial environment is known as
Ans → in vitro
Explanation →
Q. A compound possessing hydrophobic and hydrophilic groups in its structure is known as
Ans → Ampipathic
Explanation →
Q. Name the type of mutation involving the addition of one or more bases into a DNA sequence
Ans → insertion
Explanation →
Q. Small edible package made usually from gelatin or other materials that can be filled with drugs (solids or liquids) to produce a unit dose, mainly for oral use.
Ans → capsule
Explanation →
Q. Usually water or low-molecular-weight alcohols or compounds, used in topical applications and in wet granulation, for the production of tablets.
Ans → moistening agents
Explanation →
Q. On a light microscope, the lenses closest to the specimen, typically located at the ends of turrets is called as
Ans → objective lenses
Explanation →
Q. Naturally produced protein synthesis inhibitor of the lincosamide class that binds to the 50S subunit, inhibiting peptide bond formation
Ans → lincomycin
Explanation →
Q. Name a group of common sexually transmitted viruses that may be associated with genital warts or with cervical cancer
Ans → human papillomavirus (HPV)
Explanation →
Q. The movement of chemicals (drugs) into, through, and out of biological organisms or their parts.
Ans → Biotranslocation
Explanation →
Q. Artificial spherical lipid bilayer droplet formed mainly from phospholipids having a core of water phase, small enough to form a relatively stable dispersion in aqueous media and with potential use in drug delivery.
Ans → liposome
Explanation →