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Initial, typically larger than the maintenance dose of a drug given to a patient at the start of pharmacotherapy.
Pharmaceutics Pharmacist Competitive Exams
Q. Initial, typically larger than the maintenance dose of a drug given to a patient at the start of pharmacotherapy.
Ans → loading dose
Explanation →
This question is taken from the test/quiz post: one liners Pharmaceutics| B.Pharmacy| Pharmacy file-5 - attemp/practice
More oneliners in - one liners Pharmaceutics| B.Pharmacy| Pharmacy file-5
Q. Insertion or grafting of a biological, living, inert, or radioactive material into the body.
Ans → implantation
Explanation →
Q. Specific case of drug embedding in insoluble excipients (typically in a polymer) in order to achieve extended release.
Ans → matrix formulation
Explanation →
Q. Small sterile usually polymeric matrices, pellets, or particles for insertion or implanting into the body by surgical means or by injection to help achieve sustained release.
Ans → implants
Explanation →
Q. Emulsions in which the dispersed droplets are in the micron-size range.
Ans → microemulsions
Explanation →
Q. Number that expresses the reduction in the numbers of a microorganism, brought about by a sterilizaion process.
Ans → inactivation factor (IF)
Explanation →
Q. Reversible formation of association colloids from surfactants in nonpolar solvents leads to aggregates termed inverted (or inverse, reverse, or reversed) micelles.
Ans → inverted micelle
Explanation →
Q. A Solid spherical particles of micron-size range, used as matrix dosage forms.
Ans → microsphere
Explanation →
Q. Artificial spherical lipid bilayer droplet formed mainly from phospholipids having a core of water phase, small enough to form a relatively stable dispersion in aqueous media and with potential use in drug delivery.
Ans → liposome
Explanation →
Q. Concentration of a drug that must be achieved in the plasma before any desired therapeutic or pharmacological effect can be obtained.
Ans → minimum effective plasma concentration
Explanation →
Q. Initial, typically larger than the maintenance dose of a drug given to a patient at the start of pharmacotherapy.
Ans → loading dose
Explanation →
Q. Lowest concentration of an antibacterial drug necessary to inhibit the growth of a microorganism.
Ans → minimum inhibitory concentration (MIC)
Explanation →
Q. Tablet, which does not contain a disintegrant and which is sucked to dissolve in the mouth to produce either a local (e.g., antiseptic) or systemic (e.g., vitamins) effect.
Ans → lozenge
Explanation →
Q. Release of a drug from a dosage form that it is not immediate
Ans → modified release
Explanation →
More one-liners in - Pharmaceutics
Q. The deposit of a drug in a body created by injection or by a similar mode of introduction to form a source of slow release.
Ans → depot
Explanation →
Q. The disease characterized by impairment in the absorption of neutral amino acids
Ans → Hartnup’s disease
Explanation →
Q. Method by which powder particles are compressed into a large tablet, called a slug, which is subse- quently dry-screened and compressed into a tablet.
Ans → slugging
Explanation →
Q. Measure of the fraction of a given drug that is absorbed intact into the systemic circulation from a dosage form, relative to a recognized, clinically proven, standard dosage form of that drug.
Ans → relative bioavailability
Explanation →
Q. Name the most serious stage of pertussis (whooping cough), characterized by severe and prolonged coughing spells
Ans → paroxysmal stage
Explanation →
Q. Name the organism that depends on high concentrations of salt in the environment to grow
Ans → halophile
Explanation →
Q. Lipid-based chemical mediators produced by leukocytes and other tissue cells; promote inflammation and allergic responses
Ans → leukotrienes
Explanation →
Q. The ‘parent’ nucleotide synthesized in the biosynthesis of purines is
Ans → Inosine monophosphate
Explanation →
Q. Usually small, flat, and soft tablets, which are designed to be placed under the tongue to allow direct absorption of the active ingredient through the mucosa for systemic effect.
Ans → sublingual tablets
Explanation →
Q. Serious infection caused by Trypanosoma brucei and spread by the bite of the tsetse fly
Ans → human African trypanosomiasis
Explanation →
Q. Name the retrovirus responsible for acquired immune deficiency syndrome (AIDS) in humans
Ans → human immunodeficiency virus (HIV)
Explanation →
Q. Name a stage in the drying of solids, above which the drying rate is linear, at which the drying rate ceases to be linear, until it reaches the equilibrium moisture content.
Ans → critical moisture content
Explanation →
Q. A term applied to the combination of molecules of a substance with one another to form more complex systems.
Ans → association
Explanation →
Q. The Schick test is done to detect the immunity or susceptibility to _______.
Ans → Diphtheria
Explanation →
Q. Class of antibacterials that inhibit cell wall synthesis by binding to peptidoglycan subunits and blocking their insertion into the cell wall
Ans → glycopeptides
Explanation →
Q. Name the structure embedded in the dermis from which hair grows
Ans → hair follicle
Explanation →
Q. Name the antibody dimer primarily found in breast milk, mucus, saliva, and tears
Ans → IgA
Explanation →
Q. The most commonly employed technique for separation of plasma proteins
Ans → Electrophoresis
Explanation →
Q. An animal that transfers a pathogen from one host to another or from a reservoir to a host without being infected by the pathogen itself
Ans → mechanical vector
Explanation →
Q. A type of endocytosis in which extracellular ligands are targeted to specific cells through their binding to specific cell surface receptors
Ans → receptor-mediated endocytosis
Explanation →
Q. Antibodies which are capable of neutralizing the exotoxins are called ______ .
Ans → Antitoxin
Explanation →
Q. When a reaction provides the agents for a subsequent reaction.
Ans → chain reaction
Explanation →
Q. A lymphoid cells that recognize and destroy abnormal target cells by inducing apoptosis
Ans → natural killer cells (NK cells)
Explanation →
Q. A solid dosage form prepared to a desired shape, usually in large-scale production, by means of high pressure in a punch and die.
Ans → compressed tablet
Explanation →
Q. Name the hyperthyroidism caused by an autoimmune disease affecting thyroid function
Ans → Graves disease
Explanation →
Q. The process whereby a molecule is split into simpler fragments which may be smaller molecules, atoms, free radicals or ions.
Ans → dissociation
Explanation →
Q. Release of a drug from a dosage form that it is not immediate
Ans → modified release
Explanation →
Q. Opposite of deliquescence; the drying of a salt solution when the vapour pressure of water in the saturated solution of a substance is greater than the partial pressure of water in the ambient air.
Ans → efflorescence
Explanation →
Q. Trypsin hydrolyses peptide bonds, the carbonyl group of which is contributed by the amino acids
Ans → Arginine and lysine
Explanation →
Q. The lipoproteins synthesized in the intestinal mucosal cells from the absorbed lipids are
Ans → Chylomicrons
Explanation →
Q. Virus, therapeutic serum, toxin, antitoxin, or analogous product applicable to the prevention, treatment, or cure of diseases or injuries in humans and/or animals.
Ans → biological product
Explanation →
Q. A very strong attraction between two or more atoms that are sharing their electrons.
Ans → Covalent Bond
Explanation →