Pharmacology revision notes, some basic points from general pharmacology, pharmacology one liners, for pharmacy exams.
Pharmacology revision notes, some basic points from general pharmacology, pharmacology one liners, for pharmacy exams.
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binding of Morphine and Naloxone to the Opioid receptors
competitive antagonism
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When both agonist and antagonist binds reversibly on the same site of the receptor
competitive antagonism
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Antagonist binds with the same receptor as the agonist and inhibits its effect
receptor anatgonism
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When two drugs act at different receptors or by different machanisms on the same physiological system and produce opposite effect
Functional antagonism i.e insulin and glucagon on blood sugar
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Use of dimecaprol in arsenic poisoning is an example of
Chemical antagonism
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Adsorption of alkaloids by activated charcoal is an example of
Physical antagonism
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When the effect of one drug is decreased or abolished in the presence of another drug
Drug antagonism
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When two or more drugs on simultaneous administration show effect greater than that of either drug alone
Synergism (e.g. Sulphamethoxazole + trimethoprim)
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The enhancement of action of one drug by another inactive drug
Potentiation (supra-additive effect)
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the range of concentration of drug which produces desired response with minimal toxicity
Therapeutic window
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The amount of drug required to produced a desired response is called
Drug potency
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The combined effect of two or more drugs is equal to the sum of their indivisual effect
Additive effect i.e paracetamol + ibuprofen as analgesics